Menopause Masterclass: HRT Safety, Patch Absorption, Progesterone Intolerance, and Bone Density

unPAUSED with Dr. Mary Claire Haver

Mary Claire Media, LLC

Medicine, Health & Fitness, Society & Culture

4.8 • 1.2K Ratings

🗓️ 12 May 2026

⏱️ 70 minutes

🔗️ Recording | iTunes | RSS

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Summary

In this episode of unPAUSED, Dr. Mary Claire Haver answers your most asked questions about hormone therapy, menopause symptoms, and how to advocate for yourself when your doctor doesn't have answers. She walks through who actually qualifies for HRT, what the real contraindications are versus conditions that simply require a different delivery method, and how to think about continuing estrogen, progesterone, and testosterone therapy after 60. Dr. Haver explains the estrogen patch absorption problem, with research showing that up to 20 percent of women on transdermal therapy never reach physiologic estradiol levels regardless of dose. She breaks down SHBG, the protein that can bind your hormones and render them inactive even when your numbers look adequate on paper, and walks through what optimal estradiol levels look like for bone density and osteoporosis prevention specifically. Books: “The Complete Bone and Joint Health Plan: Help Prevent and Treat Osteoporosis and Arthritis,” by Jocelyn Wittstein“The New Perimenopause,” by Dr. Mary Claire Haver Resources: Women’s Health Initiative Estradiol (University of Rochester Medical Center) Meet Dr. Heather Hirsch Alloy Health Midi Health Menopause Quiz Lab Test Checklist Blueprint to close the women's health gap For full show notes, please click here. To learn more about listener data and our privacy practices visit: https://www.audacyinc.com/privacy-policy Learn more about your ad choices. Visit https://podcastchoices.com/adchoices

Transcript

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0:00.0	I'm Dr. Mary Claire Haver, a board-certified obstetrician and gynecologist and certified menopause practitioner.
0:09.1	I'm also an adjunct professor of obstetrics in gynecology at the University of Texas Medical Branch.
0:15.6	Welcome to Unpaused, the podcast where we cut through the silence and talk about what it really takes for women to thrive in the second half of life.
0:34.0	The views and opinions expressed on pause are those of the talent and guests alone and are provided for informational and entertainment purposes only.
0:42.8	No part of this podcast or any related materials are intended to be a substitute for professional medical advice, diagnosis, or treatment.
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