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Science Friday

Memories Change. But Can We Change Them On Purpose?

Science Friday

Science Friday and WNYC Studios

Natural Sciences, Wnyc, Science, Friday, Life Sciences

4.46.3K Ratings

🗓️ 14 November 2025

⏱️ 19 minutes

🧾️ Download transcript

Summary

Neuroscientists are manipulating memories in mice in an effort to develop treatments for brain disorders.

Transcript

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0:00.0

Hi, it's Ira Flato, and you're listening to Science Friday.

0:06.6

Today on this show, the malleability of memory.

0:10.6

You can't step in the same river twice.

0:12.6

I think it's the same thing with memory, that you can't exactly recall the exact same memory twice.

0:21.8

Our memories make us who we are.

0:25.0

Just ask Barbara Streisand.

0:26.9

But seriously, despite the lyrics to popular music, memories are not frozen in time.

0:33.0

When we recall memories, details shift and shape over time.

0:37.1

In fact, the latest neuroscientific research

0:39.8

shows that we can go even a step further to actually manipulate our memories and even implant

0:47.0

false ones. I know this sounds somewhat sinister, not to mention the plot of a few science fiction

0:53.0

movies. My next guest is optimistic that memory manipulation can revolutionize how we treat brain disorders.

1:00.5

Dr. Steve Ramirez is author of the new book How to Change a Memory,

1:04.1

an Associate Professor of Psychology and Brain Sciences at Boston University in Boston, Massachusetts.

1:10.4

Welcome to Science Friday.

1:11.9

Thank you so much.

1:12.9

It's awesome to be back.

1:14.2

Nice to have you back.

1:15.4

You know, I think that a lot of us think of our memories as constant, a file.

1:19.6

We can go back to retrieve it exactly as it was stored.

1:23.4

But that's not what happens, is it?

1:26.3

Yeah, we tend to think of memories nowadays as a kind of reconstruction of the past.

...

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