May 14, 2021 This Week in Cardiology Podcast
This Week in Cardiology
Medscape Podcasts
4.9 • 963 Ratings
🗓️ 14 May 2021
⏱️ 17 minutes
🧾️ Download transcript
Summary
The upcoming ACC meeting, polypharmacy, finerenone, and ethics and professionalism are the topics covered by John Mandrola, MD, in this week's podcast. https://www.medscape.com/twic
ACC Preview:
ACC.21 Looks to Repeat Success Despite Pandemic Headwinds https://www.medscape.com/viewarticle/950836
- Level and Prevalence of Spin in Published Cardiovascular Randomized Clinical Trial Reports With Statistically Nonsignificant Primary Outcomes: A Systematic Review https://pubmed.ncbi.nlm.nih.gov/31050775/
Polypharmacy
Hypertension Worsened by Commonly Used Prescription Meds https://www.medscape.com/viewarticle/950724
Finerenone
Finerenone Scores Second Pivotal-Trial Success in Diabetic Kidney Disease https://www.medscape.com/viewarticle/951027
- Effect of Finerenone on Chronic Kidney Disease Outcomes in Type 2 Diabetes https://www.nejm.org/doi/full/10.1056/NEJMoa2025845
Ethics and Professionalism
AHA/ACC Guidance on Ethics, Professionalism in Cardiovascular Care https://www.medscape.com/viewarticle/951018
- 2020 American Heart Association and American College of Cardiology Consensus Conference on Professionalism and Ethics: A Consensus Conference Report https://www.ahajournals.org/doi/10.1161/CIR.0000000000000963
Features:
Mandrola Previews the 2021 (Virtual) American College of Cardiology Scientific Sessions https://www.medscape.com/viewarticle/950797
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Questions or feedback, please contact news@medscape.net
Transcript
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| 0:00.0 | You're listening to this week in cardiology from the heart.org on medscape. |
| 0:09.7 | You can now access the latest in medical news on your Amazon Alexa enabled device. |
| 0:14.3 | Join me, Perry Wilson, every weekday morning for Medscape Medical Minute, |
| 0:18.0 | where I highlight the top medical stories of the day. |
| 0:21.1 | To add Medscape Medical Minute to your flash briefing, search for Medscape |
| 0:24.4 | Medical Minute on Amazon and click enable. Or open the Amazon Alexa app, go to |
| 0:29.0 | Skills, search for Medscape Medical Minute and click enable. Then say, |
| 0:33.4 | Alexa, what's the news or Alexa, what's my flash briefing? I hope you'll join us. |
| 0:39.8 | Hi everyone, this is John Mandrola from the Heart.org medscape |
| 0:44.0 | cardiology and this is this week in cardiology for May 14th 2021. |
| 0:50.4 | This week COVID an ACC preview, polypharmacy, Finerinone, and ethics. |
| 0:59.4 | First up of course is COVID. |
| 1:01.1 | I'm going to be very brief. It's getting better. We are almost there. I renewed my |
| 1:07.2 | passport this week. Let's move on to the ACC. It starts this weekend, as in tomorrow. Here are a few brief comments on the |
| 1:17.4 | trials that I see that are most potentially interesting. Now I always miss some, but these are the ones that stand out. The first trial to be presented is Paradise |
| 1:26.9 | MI. It's one of those big multi-centered industry-sponsored trials that compared Secubitrovas Sartan to Ramaprill in post-MI patients |
| 1:36.0 | who had both an EF less than 40% and clinical evidence for heart failure. The trial |
| 1:42.3 | also required having one risk enhancer such as age |
| 1:46.6 | greater than 70 or a fib or diabetes or prior am I etc. Now there was no run-in phase that enhances the trials generalizability and depending |
| 1:56.7 | on dosing Ramapril is a pretty legitimate comparator. Again though, I do not understand |
| 2:02.0 | why these trials are not designed to just compare |
| 2:04.7 | Sacubitrol Val-Sartan to Val-Sartan alone. |
... |
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