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This Week in Cardiology

May 12 2023 This Week in Cardiology

This Week in Cardiology

Medscape Podcasts

Medicine, Science, Health & Fitness

4.9963 Ratings

🗓️ 12 May 2023

⏱️ 25 minutes

🧾️ Download transcript

Summary

Two new papers on left atrial appendage occlusion, the promise of DNA, statins in the elderly, and SGLT2 inhibitors are the topics John Mandrola, MD, discusses in this week's podcast.

This podcast is intended for healthcare professionals only.

To read a partial transcript or to comment, visit:

https://www.medscape.com/twic

I. Listener Feedback

- When to Start a Statin Is a Preference-Sensitive Decision

https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.117.029808

II. Left Atrial Appendage Closure

LAA Closure Outcomes Improve With CCTA: Swiss-Apero Subanalysis

https://www.medscape.com/viewarticle/991623

- Impact of Preprocedural Computed Tomography on Left Atrial Appendage Closure Success: A Swiss-Apero Trial Subanalysis https://doi.org/10.1016/j.jcin.2023.02.027

- Outcomes of percutaneous left atrial appendage occlusion device implantation in atrial fibrillation patients based on underlying stroke risk https://doi.org/10.1093/europace/euad049

III. Polygenic Risk Scores

- Predictive Accuracy of a Polygenic Risk Score Compared With a Clinical Risk Score for Incident Coronary Heart Disease https://jamanetwork.com/journals/jama/fullarticle/2761086

- Cardiovascular Disease Risk Assessment Using Traditional Risk Factors and Polygenic Risk Scores in the Million Veteran Program https://jamanetwork.com/journals/jamacardiology/article-abstract/2804439

- Validity of polygenic risk scores: are we measuring what we think we are? https://doi.org/10.1093/hmg/ddz205

IV. Statins in Older Patients

High Cholesterol in Seniors: Use Statins for Primary Prevention?

https://www.medscape.com/viewarticle/991801

V. SGLT2 Inhibitors

FDA Expands Use of Dapagliflozin to Broader Range of HF

https://www.medscape.com/viewarticle/991736

- Dapagliflozin in Heart Failure with Mildly Reduced or Preserved Ejection Fraction

https://www.nejm.org/doi/full/10.1056/NEJMoa2206286

You may also like:

Medscape editor-in-chief Eric Topol, MD, and master storyteller and clinician Abraham Verghese, MD, on Medicine and the Machine

https://www.medscape.com/features/public/machine

The Bob Harrington Show with Stanford University Chair of Medicine, Robert A. Harrington, MD.

https://www.medscape.com/author/bob-harrington

Questions or feedback, please contact

news@medscape.net

Transcript

Click on a timestamp to play from that location

0:00.0

You're listening to this week in cardiology from the heart

0:03.4

org medscape cardiology this podcast is intended for health care

0:07.6

professionals only any views expressed are the presenters own and do not

0:11.2

necessarily reflect the views of WebMD or Medscape.

0:15.1

You can now access the latest in medical news on your Amazon Alexa-enabled device.

0:19.7

Join me, Perry Wilson, every weekday morning for Medscape Medical Minute where I

0:23.7

highlight the top medical stories of the day. To add Medscape Medical

0:27.4

Minute to your flash briefing search for Medscape Medical Minute on Amazon

0:31.1

and click enable or open the Amazon Alexa app go to skills

0:34.7

search for Medscape Medical Minute and click enable then say Alexa what's the

0:40.1

news or Alexa what's my flash briefing I hope you'll join us.

0:44.0

Hi everyone this is John Mandrola from the heart dot org medscape cardiology and this is

0:50.3

this week in cardiology for May 12th 2023 This week, two more papers on left-a-lapendage occlusion. The promise of DNA for prediction stands in the elderly and SGLT2 inhibitors again.

1:09.5

First, a quick thanks to Dr. Approvalve-IOS and the crew at Lehigh Valley Health for inviting me

1:15.8

to give the keynote last Saturday.

1:18.4

As always, I feel extremely grateful for these invites.

1:22.2

First, it's an honor to be asked to speak. Second, it is great to meet the young people training to do this job of cardiology, but this was a particularly fun meeting in Pennsylvania as the sessions were notable because they included such robust critical appraisal.

1:38.6

I mean sub-specialists were actually critically appraising the literature in their own field.

1:45.0

Havascular surgeon was questioning the value of operating on asymptomatic

1:50.5

karate disease.

1:52.0

An interventional cardiologist went through the studies at

1:54.6

PCI and Staple CAD and wait for it. That speaker lauded the strength of modern medical

...

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