Making a Covid-19 vaccine for two billion people
Unexpected Elements
BBC
4.4 • 570 Ratings
🗓️ 26 July 2020
⏱️ 62 minutes
🧾️ Download transcript
Summary
There's been encouraging news about the Oxford Covid-19 vaccine this week from a trial involving about 1,000 people. But how great is the challenge in scaling up from making a few thousand doses of the vaccine to manufacturing two billion by the end of this year? Sandy Douglas of Oxford's Jenner Institute explains how they plan to mass-produce the vaccine safely given the speed and magnitude of the scale up.
A new kind of treatment for Covid-19 may come from an unlikely source: llamas and alpacas, the South American relatives of the camel. Camelids produce unusually small and simple antibodies against viruses, including the coronavirus. This feature may make these molecules an effective Covid-19 therapy. Jane Chambers reports on research in Chile and the UK.
Also in the programme: what has made just a few mosquito species evolve a preference for biting humans, and the theory that 800 million years ago the Moon and the Earth were bombarded by a shower of asteroids which plunged the Earth into a global ice age - an event which changed the course of the evolution of life.
These days we're more acquainted with soap than ever before, as we lather up to help stop the spread of coronavirus. And for CrowdScience listener Sharon, this set off a steady stream of soapy questions: how does soap actually work? How was it discovered in the first place, long before anyone knew anything about germs? Are different things used for washing around the world, and are some soaps better than others?
We set up a CrowdScience home laboratory to explore the soap making process with advice from science-based beauty blogger Dr Michelle Wong, and find out what it is about soap's chemistry that gives it its germ-fighting superpowers. Soap has been around for at least 4000 years; we compare ancient soap making to modern methods, and hear about some of the soap alternatives used around the world, like the soap berries of India.
And as for the question of whether some soaps are better than others? We discover why antibacterial soaps aren't necessarily a good idea, and why putting a toy inside a bar of soap might be more important than tweaking its ingredients.
(Image: A team of experts at the University of Oxford are working to develop a vaccine that could prevent people from getting Covid-19. Credit: Press Association)
Transcript
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| 0:00.0 | In 2019, we began investigating the disappearance of Dr. Ruzha Ignatva. |
| 0:08.0 | I believe we are a very special network. |
| 0:10.0 | A scammer who stole billions from investors around the world. |
| 0:15.0 | She's on the FBI's 10 Most Wanted list. |
| 0:18.0 | And now, we have some unmissable updates. She has money and when you have |
| 0:23.0 | money you have power. Join me, Jamie Bartlett, as the hunt for the missing crypto queen continues. |
| 0:29.5 | Listen first on BBC Sounds. This is the science hour from the BBC World Service, where in half an hour |
| 0:35.8 | crowd science will be dipping into the science |
| 0:38.3 | of soap, keeping us clean since the time of the Faroes. Soap operations with Marni Chesterton |
| 0:45.1 | later in the hour on CrowdScience. Before that, you've got Science in action with me, Roland Pease. |
| 0:52.0 | Remember the asteroid impact at Chick-aicksilup near Mexico, which wiped out |
| 0:55.9 | the dinosaurs? Well, we've something much worse on the menu. Yes, if several Chicksloob-sized |
| 1:03.8 | asteroids were hitting the Earth in close proximity and time, then the global consequences would never have an opportunity to relax. |
| 1:14.6 | But where are the traces now? It all happened, if it happened at all, such a long time ago. |
| 1:21.2 | Also, we meet the scientists trying to develop a coronavirus treatment with the help of alpacas. |
| 1:30.1 | What we can make in the lab are nanobody reagents |
| 1:34.3 | that kill the live virus extremely well, |
| 1:38.0 | better than almost anything we've seen. |
| 1:40.2 | It's six months since we first covered coronavirus year on science and action. |
| 1:44.8 | Then it was a handful of worrying cases in China. |
| 1:49.1 | Now it's a global torrent. |
| 1:51.0 | 15 million already infected rising daily by 200,000 more. |
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