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Real Life Pharmacology - Pharmacology Education for Health Care Professionals

Lotrisone (Clotrimazole/Betamethasone) Pharmacology

Real Life Pharmacology - Pharmacology Education for Health Care Professionals

Eric Christianson, PharmD; Pharmacology Expert and Clinical Pharmacist

Education, Health & Fitness, Medicine

5716 Ratings

🗓️ 26 June 2025

⏱️ 14 minutes

🧾️ Download transcript

Summary

Lotrisone is a topical cream that contains a combination of clotrimazole, an antifungal, and betamethasone dipropionate, a corticosteroid.



It is used to treat fungal skin infections such as athlete’s foot, jock itch, and ringworm that also involve inflammation or itching.



Clotrimazole works by disrupting the fungal cell membrane, while betamethasone reduces redness, swelling, and itching.



Lotrisone should not be used on the face, groin, or underarms for extended periods due to the risk of skin thinning and other steroid-related side effects.

Transcript

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0:00.0

Hey all, welcome back to the Real Life Pharmacology podcast. I'm your host, Farmerist, Derek Christensen.

0:05.6

Thank you so much for listening today. Go check out Real Life Pharmacology.com. Get your free 31-page

0:12.2

PDF on the top 200 drugs. It's a great study guide, great refresher. If you're out in practice,

0:18.1

absolutely no cost to you, simply an email an email will get you access to that.

0:22.6

We'll also get you updates when we've got new podcasts available as well as other content.

0:28.1

So again, go check that out.

0:29.8

Real Life Pharmacology.com.

0:32.8

All right.

0:33.2

The drug we're going to tackle today is called Lotrozone.

0:41.8

This is a combination medication a topical agent of beta methamthosone as well as clotrimosol clitrimosol is an antifungal agent

0:49.2

beta methamethosone is a topical corticosteroid.

0:57.1

Now, where is this medication going to be used for?

1:03.8

It's going to be used in the management of athletes' foot, so fungal infection in the feet,

1:10.0

and then jock itch as well as the primary indication as well as athletes' foot that I've seen this utilized for.

1:12.6

And that's caused by a fungal infection, obviously, as well.

1:16.1

So a little bit more detail about a couple of these indications.

1:20.2

So Tinia Curis is commonly known as jock itch, again, fungal infection that affects,

1:26.9

primarily the groin area.

1:30.1

So it's kind of a red, itchy, can be ring-shaped rash in the inner thighs, groin area,

1:37.2

even progress to the buttocks area.

1:41.5

It tends to spread or it can spread, and it will have a well-defined or typically is going to have

1:47.3

a well-defined border there as well. It's kind of some of the signs and symptoms. You can have

...

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