Hey all, welcome back to the Real Life Pharmacology podcast. I'm your host, pharmacist,

Eric Christensen, and I thank you so much for listening today. As always, go check out

real-life pharmacology.com. Go subscribe there. Get your free top 200 study guide. It's a 31-page

PDF, so plenty of info there. I pulled out some of the most common things that you actually see in practice,

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So go get that for free, no cost to use, simply just an email there.

With that, let's get into the drug of the day today,

and that is Lira Glutide. Brand name in this medication is Victosa, or it is also called Saxenda.

Now, this drug is a GLP1 receptor agonist. It's mostly used in diabetes, but the Saxenda product can be used for

weight loss. Now, if you remember mechanistically, so GLP 1 or human GLP 1 is an incritin hormone within the body.

And that helps basically regulate insulin secretion and more specifically

glucose-dependent insulin secretion.

So when you eat food, blood sugar rises and we get a release of insulin to store that glucose.

So, GOP-1's help utilize that process. It also reduces glucagon secretion.

So those are two really important things for maintaining normal blood sugar and managing diabetes,

of course. In addition, Incretins have also been associated with slowing gastric emptying.

And that's probably where the benefit from weight loss or weight management comes from,

in that patients tend to feel a little bit more

full, and they may potentially eat a little less, and that's going to potentially help with

weight loss, weight management. Now, as far as a diabetes medication, the Victosa, the brand name Victosa, for their glutide.

The guidelines for diabetes have been changing.

ADA guidelines are typically what most clinicians utilize.

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