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Welcome.

This is the show where we bring science.

What that essentially means is.

Discovery is,

advances, research, technology, unbelievable. Without further ado, this. answers. Research. Technology.

Unbelievable.

Without further ado, this is the Naked Scientists.

Hello, welcome to this week's Naked Scientists, the program where we strive to bring you the latest

breakthroughs in science, technology and medicine.

I'm Chris Smith.

Coming up, could lab-grown mini-guts help us to crack Crohn's disease?

Also, is the universe organized a bit like a bagel? Well I talk to one cosmologist who's trying to figure it out and we hear from the engineers who've recreated a 115 year old cricketing contraption that actually bowled out an Australian legend back in the day.

From Cambridge University's Institute of Continuing Education, this is the naked scientists. Up first this week, mini guts, grown from cells collected from the linings of the intestines of patients with the

inflammatory bowel condition, Crohn's disease, are helping scientists to better understand why some people develop this chronic and disabling

syndrome.

Matius Zilbau, who's professor of pediatric gastrointestinalology at the University of Cambridge,

has found changes in the level of activity of genes linked to how the gut

lining cells interact with the immune system. This is down to a system called

epigenetics and it involves chemical groups being added to the DNA to alter

...