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Kids Next For Pfizer Vaccine, Side-Channel Surveillance, Medical Maggots. Oct 29, 2021, Part 1

Science Friday

Science Friday and WNYC Studios

Science, Life Sciences, Wnyc, Natural Sciences, Friday

4.4 • 6.3K Ratings

🗓️ 29 October 2021

⏱️ 47 minutes

🧾️ Download transcript

Summary

Younger Kids Next In Line For COVID-19 Vaccines

This week, an FDA advisory panel voted unanimously to recommend that the COVID-19 vaccine made by Pfizer vaccine be approved for children as young as 5. If the FDA concurs and the CDC agrees, lower-dose Pfizer vaccinations could soon be available for children ages 5 to 11, via local pediatricians. Just who will be immediately eligible for the doses, and how vaccinating young children might affect school mask policies and other restrictions, remains to be seen.

Umair Irfan, staff writer at Vox, joins Sophie Bushwick to talk about the news and other stories from the week in science, including potential COVID-related criminal charges against Brazil’s Jair Bolsonaro, an experimental bionic vision implant, and the possible discovery of an exoplanet in the galaxy Messier 51.

Could Ordinary Household Objects Be Used To Spy On You?

In the movies, if a room is bugged, the microphone might be hidden in a potted plant. But in recent years, researchers have come up with ways to use the trembling leaves of a potted plant, light glancing off a potato chip bag, and even tiny jiggles in the head of a spinning hard drive caused by a nearby conversation to be able to listen to what’s happening in a room, or to gain information about what’s going on nearby.

On a larger scale, other researchers have been able to use the vibrations of an entire building to paint a picture of movements within it—and even the health status of the people inside.

The approach is known as a side-channel attack: Rather than observing something directly, you’re extracting information from something else that has a relationship with the target. Many of the approaches are not straightforward—they require an understanding of the physics involved, and sometimes heavy data-processing or machine learning to interpret the hazy information yielded by these techniques.

Jon Callas of the Electronic Frontier Foundation, Hae Young Noh of Stanford, and Kevin Fu of the University of Michigan join host Sophie Bushwick to talk about the risks and opportunities afforded by these sneaky methods of surveillance, and how concerned you should be.

A Maggot Revolution In Modern Medicine

In a bloody battle during World War I, two wounded soldiers were stranded on the battlefield in France, hidden and overlooked under some brush. Suffering femur fractures and flesh wounds around their scrotum and abdomen, they lay abandoned without water, food, or shelter for a whole week. At the time, outcomes for these kinds of wounds were poor: Patients with compound femur fractures had a 75 to 80% mortality rate. By the time the soldiers were rescued and brought to a hospital base, orthopedic surgeon William Baer expected their wounds to be festering, and their conditions fatal. But much to his surprise, neither showed any signs of fever, septicaemia, or blood poisoning.

When his team removed the soldiers’ clothing, they discovered that their flesh wounds were filled with thousands of maggots, or baby flies—little larvae with a massive appetite for decaying matter. Baer was repulsed by the sight, and the team quickly washed off the wriggling maggots. Underneath, instead of the expected pus and bacteria-infected flesh, Baer marveled over “the most remarkable picture.”

“These wounds were filled with the most beautiful pink granulation tissue that one could imagine,” Baer later wrote in a 1931 report in the Journal of Bone and Joint Surgery. Maggots have long been associated with death, but in this case, they were helping the soldiers stay alive. As these insects were simply tucking in for their typical meal of dead, decaying flesh, they were inadvertently aiding the soldiers by cleaning their wounds, keeping infection at bay. The soldiers recovered—saved by their tiny, wriggling “friends which had been doing such noble work,” Baer wrote.

Baer’s paper is one of the first reports of maggots used in medicine, but these insects have been found healing wounds for thousands of years, with references in the Old Testament and in ancient cultures of New South Wales and Northern Myanmar.

Read the rest on sciencefriday.com.

Transcript

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0:00.0

This is Science Friday. I'm Sophie Bushwick, Technology Editor at Scientific American,

0:04.9

and this week I'm sitting in for Ira Flato. Later in the hour, what biomedical researchers are

0:10.8

learning about the medical miracle of maggot therapy? Yes. And ways to listen or watch that you

0:18.1

may not expect is your potato chip bag giving you away? But first, progress towards COVID vaccines

0:25.4

continues for younger and younger people, with an FDA advisory panel voting unanimously to

0:31.5

recommend that the Pfizer vaccine be approved for children as young as five. Vox staff writer Umar

0:38.0

or Fawn is here with more on that and other stories from this week in science. Welcome back Umar.

0:43.9

Thanks for having me, Sophie. So this week COVID vaccines for kids got a step closer. Umar,

0:50.3

what's the latest? This advisory committee to the Food and Drug Administration that looks

0:55.2

independently at this data basically concluded that the benefits for this vaccine outweigh the risks

1:01.0

in ages 5 to 11. This is the Pfizer BioNTech vaccine that's already has full FDA approval for adults

1:09.2

and now this moves this to a lower age bracket which could potentially include upward of 28

1:14.3

million children and these shots could potentially start rolling out as soon as early next week.

1:20.4

Will kids be getting the same dose adults did and the same way that adults did?

1:25.4

No, they will not. So one of the critical things they did in this clinical trial is that they

1:29.5

used a lower dose. They wanted to measure and ensure that children were still generating the same

1:35.4

immune response as adults, but they wanted to use a lower level of the inoculum because they

1:40.0

wanted to minimize the amount of side effects that were potentially could occur. And you know,

1:45.9

a lot of doctors and scientists will tell you children are not little adults and so they wanted

1:49.6

to make sure that they started from scratch and made sure they had a dosing that was actually

1:54.5

optimal. And so with this one third level dose still administered as two doses space three weeks

1:59.7

apart, they found that they could generate a similar level of immune response in children as they

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