4.6 • 1.5K Ratings
🗓️ 2 January 2026
⏱️ 9 minutes
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| 0:00.0 | What if just two cigarettes today raised your risk of heart failure by 50% and your risk of dying from any cause by 60%? |
| 0:08.0 | Would you still light up? |
| 0:10.0 | Welcome to Dr. Mercola's cellular wisdom. Stay informed with quick, easy-to-listen summaries of our latest articles, perfect for when you're on the go. |
| 0:18.0 | No reading required. Subscribe for free at Mercola.com for the latest health |
| 0:22.5 | insights. Hello, and welcome to Dr. Mercola's cellular wisdom. I'm Ethan Foster, and today we're |
| 0:29.5 | unpacking new evidence showing there is no safe level of smoking, not even two to five cigarettes a day. |
| 0:36.0 | We'll walk through what researchers tracked across more than 300,000 adults, |
| 0:40.3 | why reducing from a pack to a couple a day doesn't lower risk, the way many assume, |
| 0:45.3 | and how quitting begins to reverse damage over time. |
| 0:48.3 | I'm Alara Sky. |
| 0:50.3 | You're going to hear clear numbers, defined outcomes, and practical steps you can act on. |
| 0:55.6 | We'll explain how the study measured risk, what it means for heart disease, atrial fibrillation, heart failure, and all-cause mortality, |
| 1:04.8 | and why vaping belongs in this conversation because of its documented ties to chronic obstructive pulmonary disease. |
| 1:14.6 | The analysis pooled 22 long-term studies, following 323,826 adults for up to 19.9 years. |
| 1:21.6 | Across more than 25 million person years, there were 125,04 deaths and 54,078 cardiovascular events, including |
| 1:32.2 | coronary disease, stroke, atrial fibrillation, and heart failure. Participants were |
| 1:38.3 | grouped as never, former, or current smokers, with cigarette use ranging from two to five per day up to more than 20. |
| 1:46.4 | To estimate risk, researchers used Cox proportional hazard models and examined three levers, |
| 1:52.6 | pack years, cigarettes per day, and years since quitting. The primary outcomes were cardiovascular |
| 2:00.1 | disease categories and all-caused mortality. |
| 2:03.6 | Hazard ratios quantified how much risk rose compared with never smoking. |
| 2:08.6 | Here is what stands out. |
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