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The Human Upgrade: Biohacking for Longevity & Performance

Just 1 Gram Activates Your Deep Focus Switch (Take THIS) : 1484

The Human Upgrade: Biohacking for Longevity & Performance

Dave Asprey

Brain, Hacking, Fat, Education, Meditation, Self-improvement, Health & Fitness, Fasting, Nutrition, Biohacking, Wellness, Lifestyle, Fitness, Diet, Science

4.67.4K Ratings

🗓️ 14 June 2026

⏱️ 17 minutes

🧾️ Download transcript

Summary

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Try Danger Coffee: https://dangercoffee.com/

Try Suppgrade Labs: https://shopsuppgradelabs.com/


Over the last 15 years, I’ve built companies and spent millions testing what actually upgrades human performance, and I can tell you that mental fatigue has absolutely nothing to do with willpower. In this video, I break down the exact neurochemistry of deep focus. When your brain runs out of dopamine, norepinephrine, and acetylcholine, or gets bogged down by oxidative stress, your executive function collapses. The pharmaceutical industry wants you hooked on expensive stimulants that only treat the symptoms, but the real biological fix is a common antioxidant: Vitamin C.


I explain how your brain hoards Vitamin C at levels 100 times higher than your blood, how to bypass the blood-brain barrier using SVCT2 transporters, and why eating sugar before you take it completely blocks its absorption. You'll also learn the exact biohacking stack—including NAC, CoQ10, PQQ, and L-theanine—you need to recycle this molecule, protect your mitochondria, and maintain effortless, razor-sharp focus all day long.


Thank you to our sponsors!

-KILLSwitch | If you’re ready for the best sleep of your life, order now at https://www.switchsupplements.com/and use code DAVE for 20% off

-Viome | Check it out at viome.com and use code 10DAVE for 10% off. It’s time to stop guessing and start knowing your body.

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Timestamps:

00:00 – Trailer

00:21 – Focus Is Biology

01:53 – Brain Chemistry Explained

05:33 – Vitamin C Revealed

07:09 – How to Dose

08:18 – Absorption Barriers

09:31 – Optimize Uptake

10:00 – Oxidative Stress Problem

11:00 – Stack for Deeper Focus


Connect with Dave Asprey!


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The Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ https://m.facebook.com/Thehumanupgrade/


Danger Coffee: https://dangercoffee.com/DAVE15

Dave Asprey’s BEYOND Conference: https://beyondconference.com/

Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/

Dave's favorite supplements: https://www.shopsuppgradelabs.com/discount/DAVE15

Upgrade Labs: https://upgradelabs.com

40 Years of Zen: https://40yearsofzen.com

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Transcript

Click on a timestamp to play from that location

0:00.0

How many nights have you stared at the ceiling, counting the hours until morning?

0:05.0

Maybe you try to sleep supplement, but it knocked you out and left you groggy, like you traded one problem for another.

0:11.0

Poor sleep doesn't just make you tired. It kills your performance, slows your brain down, and speeds up aging.

0:18.0

Kill Switch from Switch supplements solves that problem. It works with your biology

0:22.9

instead of against it. It contains five gut-friendly, extensively researched ingredients like

0:29.0

Gaba, magnesium glycinate, and tart cherry extract to help you fall asleep naturally, stay asleep,

0:34.6

and wake up clear. And it's in the form of a delicious, sugar-free,

0:39.0

no-b-s-hot-coco drink. Sleep tracking data proves how well it works. People consistently hit 90-plus

0:46.1

sleep scores and more than double their REM sleep in only three days with KillSwitch. If you're

0:51.8

ready for the best sleep of your life, order now at Switch Supplements.com

0:56.1

and use code Dave for 20% off. If you don't sleep better, you get your money back. Kill Switch

1:02.2

works with your biology. Your body does the rest. Over the last 15 years, I built multiple

1:10.2

companies done more than a billion in revenue,

1:12.4

written nine bestselling books, including your Times bestsellers, and spent millions testing

1:17.9

what really upgrades human performance.

1:20.6

And here's what no one's going to tell you.

1:22.3

Focus is not a discipline problem.

1:24.6

Even the smartest, most driven people lose focus for one simple reason.

1:29.3

Their brains burn through a key molecule faster than your body can replace it. When that molecule

1:34.2

drops, your reaction time slows, you get more tired, you get mental fatigue, and no amount

1:38.9

of willpower or trying will bring your focus back because it's biology. There's a common

1:43.1

vitamin that refills this molecule fast.

...

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