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This Week in Cardiology

July 14 2023 This Week in Cardiology

This Week in Cardiology

Medscape Podcasts

Medicine, Science, Health & Fitness

4.9963 Ratings

🗓️ 14 July 2023

⏱️ 28 minutes

🧾️ Download transcript

Summary

Carotid stents, the paclitaxel story now closed, inclisiran, DOAC failures, and primary vs secondary prevention are the topics John Mandrola, MD, covers in this week's podcast.

This podcast is intended for healthcare professionals only.

To read a partial transcript or to comment, visit:

https://www.medscape.com/twic

I. Carotid Stenting CMS Proposal

Expanded Coverage of Carotid Stenting in CMS Draft Proposal

https://www.medscape.com/viewarticle/994315

No Added Benefit From Revascularization in Low-Risk CAS

https://www.medscape.com/viewarticle/992524

- Percutaneous Transluminal Angioplasty (PTA) of the Carotid Artery Concurrent with Stenting https://www.cms.gov/medicare-coverage-database/view/ncacal-decision-memo.aspx?proposed=Y&NCAId=311

- Second asymptomatic carotid surgery trial (ACST-2): a randomised comparison of carotid artery stenting versus carotid endarterectomy

https://doi.org/10.1016/S0140-6736(21)01910-3

- SPACE-2 https://journals.sagepub.com/doi/10.1177/1747493019833017

- Rationale, Design, and Implementation of Intensive Risk Factor Treatment in the CREST2 Trial 10.1161/STROKEAHA.120.030730

II. Paclitaxel

FDA: No Excess Mortality Risk From Paclitaxel Stents, Balloons for Peripheral Intervention https://www.medscape.com/viewarticle/994253

- FDA Statement https://www.fda.gov/medical-devices/letters-health-care-providers/update-paclitaxel-coated-devices-treat-peripheral-arterial-disease-unlikely-increase-risk-mortality?utm_medium=email&utm_source=govdelivery#_FDA_Actions

III. Inclisiran

FDA Expands Inclisiran Statin-Adjunct Indication to Include Primary Prevention https://www.medscape.com/viewarticle/994185

- ORION 10-11 Two Phase 3 Trials of Inclisiran in Patients with Elevated LDL Cholesterol https://www.nejm.org/doi/10.1056/NEJMoa1912387

- Effect of inclisiran on lipids in primary prevention: the ORION-11 trial

https://doi.org/10.1093/eurheartj/ehac615

- Inclisiran and cardiovascular events: a patient-level analysis of phase III trials https://pubmed.ncbi.nlm.nih.gov/36331326/

IV. DOAC Failure

Association of Alternative Anticoagulation Strategies and Outcomes in Patients With Ischemic Stroke While Taking a Direct Oral Anticoagulant

https://doi.org/10.1212/WNL.0000000000207422

V. Primary or Secondary Prevention

You may also like:

Medscape editor-in-chief Eric Topol, MD, and master storyteller and clinician Abraham Verghese, MD, on Medicine and the Machine

https://www.medscape.com/features/public/machine

The Bob Harrington Show with Stanford University Chair of Medicine, Robert A. Harrington, MD.

https://www.medscape.com/author/bob-harrington

Questions or feedback, please contact news@medscape.net

Transcript

Click on a timestamp to play from that location

0:00.0

You're listening to this week in cardiology from the heart

0:03.4

org medscape cardiology this podcast is intended for health care

0:07.6

professionals only any views expressed are the presenters own and do not

0:11.2

necessarily reflect the views of WebMD or Medscape.

0:15.1

You can now access the latest in medical news on your Amazon Alexa-enabled device.

0:19.7

Join me, Perry Wilson, every weekday morning for Medscape Medical Minute where I

0:23.7

highlight the top medical stories of the day. To add Medscape Medical

0:27.4

Minute to your flash briefing search for Medscape Medical Minute on Amazon and

0:31.5

click enable or open the Amazon Alexa app go to skills

0:34.7

search for Medscape Medical Minute and click enable then say Alexa what's the

0:40.1

news or Alexa what's my flash briefing I hope you'll join us.

0:44.0

Hi everyone this is John Mandrola from the heart dot org medscape

0:49.0

and this is this week in cardiology for July 14th 2023 this week This week,

0:55.0

let's talk, Corrotted Stents, increased death story with Pacletaxle,

1:01.0

In Cliceran,, Doak failures, and the issue of primary versus secondary prevention.

1:09.0

Okay, so first topic is that CMS published this week a proposed decision memo regarding the coverage

1:16.6

of carotid artery stenting.

1:19.7

This is a big deal for interventional doctors, vascular surgeons, and even primary care doctors who

1:26.2

may be doing a carotid screening, vascular screening.

1:31.5

Corotary stenting has now been covered in this proposed memo for patients who have

1:37.0

symptomatic disease greater than 50 percent and for patients with asymptomatic disease greater than 70% lesions.

1:45.0

They did have specific requirements for imaging and the shared decision-making

...

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