Journal Review in Bariatric Surgery: SPLENDID and BRAVES Studies

Behind The Knife: The Surgery Podcast

Science, Health & Fitness, Medicine, Education

4.8 • 1.4K Ratings

🗓️ 18 May 2023

⏱️ 26 minutes

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Summary

For our last submission as the BTK Bariatric Surgery Team, we thought we would take a minute to review some recent landmark trials in bariatric surgery. Get caught up on the impact of bariatric surgery on obesogenic cancers and non-alcoholic steatohepatitis.

Journal articles:
Association of Bariatric Surgery with Cancer Risk and Mortality in Adults with Obesity: https://pubmed.ncbi.nlm.nih.gov/35657620/.

Bariatric-Metabolic Surgery versus Lifestyle Intervention plus Best Medical Care in Non-Alcoholic Steatophepatitis (BRAVES): A Multicentre, Open-Label, Randomised Trial: https://pubmed.ncbi.nlm.nih.gov/37088093/.

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Please visit https://behindtheknife.org to access other high-yield surgical education podcasts, videos and more.

If you liked this episode, check out other bariatric episodes here: https://behindtheknife.org/podcast-category/bariatric/

Transcript

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0:00.0	Behind the Night, the surgery podcast, relevant and engaging content designed to help you dominate the day.
0:13.0	Welcome to another episode of Behind the Night.
0:25.0	We are the Barry Beatrix Center at the University of Nebraska Medical Center in Omaha, Nebraska.
0:31.0	And we have really enjoyed being the Barry Beatrix team talking to you through podcasts over the last several years.
0:39.0	I'm Dr. Corey McBride, and I am the director of MIS and Barry Atrix Surgery.
0:44.0	And I'm joined today by two of my partners, Dr. Tiffany Tanner and Dr. Ivy Haskins.
0:50.0	Today we wanted to talk about two very important articles that were recently published, the Splendid and Brave Studies.
0:57.0	Both of these trials look at how bariatric surgery impacts medical comorbidities.
1:02.0	First, let's talk about the Splendid Trail.
1:04.0	obesity can have a profound impact on multiple medical comorbidities, including increasing the risk of cancer.
1:11.0	Corey, can you tell us more about this study?
1:14.0	I'd be happy to. This is really one of the pivotal studies that was published within the last year.
1:20.0	And it comes out of the Cleveland Clinic, and Dr. Ali Aminion is the lead author.
1:25.0	Dr. Aminion is actually very known in this body of literature for articles like this, where they have compared the bariatric patients from the Cleveland Clinic health care system to weight and similarly matched patients who have not had surgery.
1:43.0	And looked at outcomes.
1:45.0	But last year they published a similar trial to this one looking at major adverse cardiac events.
1:51.0	And if you haven't read that article, I would also encourage you to do so.
1:55.0	This article, however, that was published recently, it was called the Splendid Trial, which stood for the surgical procedures and long-term effectiveness in neoplastic disease, incident, and death.
2:07.0	And with a long name like that, I understand why they called it Splendid.
2:11.0	But they followed the similar pattern that they used in previous studies, where they had a matched cohort.
2:17.0	They took all of the patients who were between 18 and 80 years old, with a BMI of 35 to 50, who had undergone bariatric surgery at the Cleveland Clinic health care system, over about a 13 year period of time.
2:31.0	And after some exclusions that came to about 3,000 patients.
	...

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