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The Life Scientific

John Gurdon

The Life Scientific

BBC

Society & Culture, Personal Journals, Science

4.61.4K Ratings

🗓️ 18 December 2012

⏱️ 28 minutes

🧾️ Download transcript

Summary

Sir John Gurdon talks to Jim al-Khalili about how coming bottom of the class in science was no barrier to winning this year's Nobel Prize for Physiology or Medicine. We're familiar with Dolly the Sheep but many people find the idea of cloning humans rather disturbing. It seems to cut to the core of who we are; but, scientifically speaking, we are getting closer to a time when cloning people might be possible. John Gurdon gives it fifty years. After a famously bad school report for science, he won the Nobel Prize for cloning a frog, decades before Dolly the Sheep. He talks to Jim al-Khalili about his pioneering work on cloning and where it all might lead.

Transcript

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0:00.0

Once you've wrapped up this podcast, how about trying a very British cult?

0:06.0

What happens if the person you trust with your future isn't what you think they are?

0:10.0

I did feel the whole time he was watching me Yeti. I saw a footprint and that really gave me gusmas.

0:16.4

Or people who knew me. Emme, I remember every secret, every lie. I'm the only one who knows the truth.

0:23.0

Discover more of our biggest podcast from 2003.

0:27.0

Listen on BBC Sounds.

0:29.0

Thank you for downloading The Life Scientific from BBC Radio 4.

0:34.0

Decades before scientists at Edinburgh University

0:37.8

cloned Dolly the Sheep, another British scientist,

0:41.0

Professor John Gerden, cloned a frog.

0:45.0

Working in his lab in Cambridge in the early 60s, John developed the techniques and some of the

0:49.6

tools that have since been used to clone not just Dolly the sheep, but mice, cats, goats and cows.

0:57.0

Even a wild ox called Noah rescued from the brink of extinction.

1:02.0

And this year, a full half a century later,

1:05.1

he was awarded the Nobel Prize for physiology or medicine

1:08.8

together with Shinya Yamanaka.

1:11.4

Dolly the sheep hogged the news headlines in 1997, but John Gurdon got there first, cloning a frog

1:17.6

from an adult cell over three decades earlier, less cuddly perhaps but proof of principle nevertheless.

1:25.0

Long before people talked about stem cells, he showed that all cells,

1:29.0

whether they are skin, heart, nerve cells, or in the case of his frog, from the intestines, contain all the genetic

1:36.5

information they need to become, well, absolutely anything.

1:40.6

And in so doing, he raised the possibility that scientists might one day be able to turn back time,

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