Jim Segermark-InSitubiologics- Offering a Non-Opioid, Long-Lasting, Biohydrogel Painkiller
Finding Genius Podcast
Richard Jacobs
4.4 • 1K Ratings
🗓️ 4 September 2018
⏱️ 29 minutes
🧾️ Download transcript
Summary
Jim Segermark is the CEO of InSitu Biologics, a biotech company using hydrogel technology to offer post-operative patients with the option of a non-opioid regional painkiller. Composed of three compounds found naturally in the body, the gel is injected with bupivacaine, which is then pushed out by water over time and released into the body, providing for three to five days of a complete analgesic effect on the area of pain. Once the bupivacaine has been released entirely, the body easily metabolizes the gel within about two weeks.
Though it has not yet been tested in human clinical trials, this biohydrogel has shown to be effective in the laboratory and holds promise for post-op patients who want fast, effective, long-lasting, and opioid-free pain relief.
Segermark discusses the potential applications of this new product, which include using the gel as a vehicle for birth control and erectile dysfunction medication rather than bupivacaine, and custom-tailoring the gel to release multiple medications at certain times and for specific durations, thereby meeting the needs of patients on an individual basis.
Tune in for the full conversation, and visit www.insitubiologics.com to learn more.
Transcript
Click on a timestamp to play from that location
| 0:00.0 | Welcome to Almost Here, Around the Corner of Future Technology Podcasts with Richard Jacobs. |
| 0:07.0 | Future Technologies is to transform our lives for better or worse or the focus of this podcast. |
| 0:13.0 | Almost here means these technologies are now here and starting to be used. |
| 0:17.0 | Or just around the corner, for Bitcoin to artificial intelligence, |
| 0:21.0 | 3D printing, blockchain, virtual reality, and more. |
| 0:25.0 | Hello, this is Richard Jacobs for the Future Tech Podcast. My guest today is Jim Segermark, |
| 0:31.6 | the CEO of In Sichu Biologics. |
| 0:34.4 | The website is In situ Biologics. |
| 0:37.3 | Jim, how you today? |
| 0:39.3 | I'm very good. |
| 0:40.3 | Glad to be here. |
| 0:41.3 | Thank you for the invitation. |
| 0:42.3 | Yeah. Well, tell me about your company. What's the premise of it? |
| 0:45.8 | Yeah, so we are a material-based technology that was originally created by scientists at the Cleveland Clinic Foundation. |
| 0:55.0 | And back in 2002 they started working on it. |
| 0:58.0 | So when you do the math, that's quite a while ago. |
| 1:01.0 | And they could envision bringing these three compounds together that are |
| 1:05.1 | found naturally in the body and creating a gel but they had a real hard time |
| 1:10.0 | making it kind of like alchemy you know you can think of these things but when they all come together |
| 1:15.8 | hit and miss so over the years they partnered with industry and by 2007 five years later the gel could be made and a lot of you know hydro gels have |
| 1:27.7 | been around people tried to do this back to the 80s and it's really never worked. |
| 1:34.0 | But this one does and it uses hyalioronic acid, |
... |
Please login to see the full transcript.
Disclaimer: The podcast and artwork embedded on this page are from Richard Jacobs, and are the property of its owner and not affiliated with or endorsed by Tapesearch.
Generated transcripts are the property of Richard Jacobs and are distributed freely under the Fair Use doctrine. Transcripts generated by Tapesearch are not guaranteed to be accurate.
Copyright © Tapesearch 2026.