Jan 13 2023 This Week in Cardiology
This Week in Cardiology
Medscape Podcasts
4.9 • 963 Ratings
🗓️ 13 January 2023
⏱️ 25 minutes
🧾️ Download transcript
Summary
FOURIER authors' response, a possible practice-changing paper in electrophysiology, and the ATLAS and CAPLA trials are the topics John Mandrola, MD, discusses in this week's podcast.
This podcast is intended for healthcare professionals only.
To read a partial transcript or to comment, visit: https://www.medscape.com/twic
I. FOURIER Authors Respond
Recount of FOURIER Data Finds Higher Mortality With Evolocumab; Trialists Push Back https://www.medscape.com/viewarticle/986634
- Restoring mortality data in the FOURIER cardiovascular outcomes trial of evolocumab in patients with cardiovascular disease: a reanalysis based on regulatory data https://bmjopen.bmj.com/content/12/12/e060172
- Letter to the Editor RE: "Restoring mortality data in the FOURIER cardiovascular outcomes trial of evolocumab in patients with cardiovascular disease: a reanalysis based on regulatory data". BMJ Open https://bmjopen.bmj.com/content/12/12/e060172.responses#letter-to-the-editor-re-restoring-mortality-data-in-the-fourier-cardiovascular-outcomes-trial-of-evolocumab-in-patients-with-cardiovascular-disease-a-reanalysis-based-on-regulatory-data-bmj-open-2022123060172
- Risk of selection bias assessment in the NINDS rt-PA stroke study https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9202115/
- Methodological survey of missing outcome data in an alteplase for ischemic stroke meta-analysis https://doi.org/10.1111/ane.13656
II. A Potential Practice-Changing Paper in Cardiac Pacing
Novel 'Cure' May Avert Lead Extraction in CIED Pocket Infections https://www.medscape.com/viewarticle/986762
- Regional Antibiotic Delivery for Implanted Cardiovascular Electronic Device Infections https://doi.org/10.1016/j.jacc.2022.10.022
- Treatment of Localized Implantable Cardiac Device Pocket Infections https://doi.org/10.1016/j.jacc.2022.11.018
III. ATLAS Trial
- Perioperative Safety and Early Patient and Device Outcomes Among Subcutaneous Versus Transvenous Implantable Cardioverter Defibrillator Implantations https://doi.org/10.7326/M22-1566
- Subcutaneous or Transvenous Defibrillator Therapy https://www.nejm.org/doi/full/10.1056/NEJMoa1915932
- Subcutaneous or Transvenous Defibrillator Therapy https://www.nejm.org/doi/10.1056/NEJMc2034917
IV. CAPLA Published
CAPLA Shows Limits of Further Ablation Post PVI in Persistent AF https://www.medscape.com/viewarticle/986901
- Effect of Catheter Ablation Using Pulmonary Vein Isolation With vs Without Posterior Left Atrial Wall Isolation on Atrial Arrhythmia Recurrence in Patients With Persistent Atrial Fibrillation https://jamanetwork.com/journals/jama/fullarticle/2800186
- Catheter Ablation for Persistent Atrial Fibrillation https://jamanetwork.com/journals/jama/fullarticle/2800200
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Questions or feedback, please contact
news@medscape.net
Transcript
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| 0:00.0 | You're listening to this week in cardiology from the heart |
| 0:03.4 | org medscape cardiology this podcast is intended for health care |
| 0:07.6 | professionals only any views expressed are the presenters own and do not |
| 0:11.2 | necessarily reflect the views of WebMD or Medscape. |
| 0:15.1 | You can now access the latest in medical news on your Amazon Alexa-enabled device. |
| 0:19.7 | Join me, Perry Wilson, every weekday morning for Medscape Medical Minute where I |
| 0:23.7 | highlight the top medical stories of the day. To add Medscape Medical |
| 0:27.4 | Minute to your flash briefing search for Medscape Medical Minute on Amazon and |
| 0:31.5 | click enable or open the Amazon Alexa app go to skills |
| 0:34.7 | search for Medscape Medical Minute and click enable then say Alexa what's the |
| 0:40.1 | news or Alexa what's my flash briefing I hope you'll join us. |
| 0:45.4 | Hi everyone this is John Mandrola from the heart.org medscape |
| 0:51.2 | and this is this week in cardiology for January 13th, 2023. |
| 0:57.0 | This week I'll cover the FOIA author's response to last week's |
| 1:03.0 | BMJ Open article, a possible practice changing paper |
| 1:08.5 | in cardiac pacing and electrophysiology, |
| 1:11.1 | a lesson in biased trial design and the Kepler study is published. |
| 1:18.0 | First up is the four-year reanalysis. Last week I reported on a provocative paper in the |
| 1:25.4 | BMJ Open Journal which reanalyzed death outcomes in the placebo-controlled |
| 1:30.5 | forre trial of the PCS K9 inhibitor Evelocumab. |
| 1:35.0 | Now the authors who are part of a group called R IAT |
| 1:41.0 | restoring invisible and abandoned trials. |
... |
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