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Psychiatry & Psychotherapy Podcast

Is Depression a Chemical Imbalance?

Psychiatry & Psychotherapy Podcast

David J Puder

Science, Health & Fitness, Medicine

4.81.3K Ratings

🗓️ 19 August 2022

⏱️ 63 minutes

🧾️ Download transcript

Summary

In this episode, we welcome back Dr. Michael Cummings to discuss a new study that explores the idea that depression may not be merely a chemical imbalance. This episode covers the origin of belief in the connection of depression with a chemical imbalance, the new study that has created questions surrounding the efficacy of antidepressants, and a holistic view on the treatment of depression.

Link to Blog.

Transcript

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0:00.0

Hello and welcome to the Psychiatry and Psychothermic Podcast.

0:12.2

I'm here to talk about getting rid of burnout, increasing job satisfaction, and feeling

0:16.6

like an expert in what you do.

0:18.6

One thing that created a lot of burnout and angst for me was trying to get continued

0:21.7

medical education right at the last minute.

0:24.2

So why not join the CME membership and do CME while listening to this podcast?

0:28.6

Go to Psychiatrypodcast.com, sign up, sign in, take the test, and the certification

0:32.6

is emailed to you in seconds.

0:34.6

All right, welcome back to the podcast.

0:36.8

I am joined today with Dr. Cummings, Dr. Cummings, and I have no conflicts of interest.

0:42.9

Dr. Cummings, welcome back to the show.

0:44.9

Hello.

0:45.9

Glad to be back.

0:47.9

Indeed, it should be an interesting show today.

0:51.1

Yeah.

0:52.1

Today we're going to be talking about a recent paper that came out in Nature magazine.

0:57.6

It was titled The Serotonin Theory of Depression, A Systematic Umbrella Review of the Evidence

1:06.3

by Monster Chef at all, just 2022.

1:12.6

And in this article, the author concludes the main area of serotonin research provide

1:18.7

no consistent evidence of their being an association between serotonin and depression

1:25.6

and no support for the hypothesis that depression is caused by lower serotonin activity or concentrations.

1:33.7

Further, he says some evidence was consistent with the possibility that long-term antidepressant

...

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