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What Next | Daily News and Analysis

Inside a COVID-19 Vaccine Trial

What Next | Daily News and Analysis

Slate Podcasts

News, News Commentary, Daily News

4.32.4K Ratings

🗓️ 14 May 2020

⏱️ 20 minutes

🧾️ Download transcript

Summary

All around the world, scientific research has been put on hold to concentrate resources on one thing: a vaccine for COVID-19. The usual red tape that slows down these experiments has been removed. And at a lab in Baltimore, researchers are working around the clock to recruit trial participants, prepare vaccine doses, and study results. 

Guest: Dr. Kirsten Lyke, lead investigator on COVID-19 vaccine trials at the University of Maryland’s Center for Vaccine Development and Global Health. 

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Transcript

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0:00.0

When I called up Dr. Kirsten-like, she'd set aside precisely 30 minutes for us to talk.

0:11.1

She ended up giving me 38.

0:13.0

But still, she was in a hurry.

0:15.2

Were you just doing vaccinations a couple hours ago?

0:19.1

I was doing vaccinations about 120 seconds ago, actually.

0:24.6

Two minutes ago, and I just ran over from the vaccination area.

0:30.0

Kirsten is running one of the coronavirus vaccine trials that have cropped up around the country.

0:34.8

Her labs at the University of Maryland.

0:36.9

And this work, it's not like any

0:39.0

other experiment she's run before. Her vaccines are at the very earliest phase of human testing.

0:44.7

It's called phase one. You know, a straightforward phase one study is usually 40 people,

0:52.1

40, 50 people.

0:53.4

40 subjects or like 40 scientists? 40, 50 people. 40 subjects or like 40 scientists?

0:56.2

40 to 50 subjects, volunteers who agreed to participate.

1:01.6

And it may take anywhere from 12 to 18 months from the time we decide to do a study to ramp it up.

1:16.8

How does that compare to what you're doing now?

1:19.5

So I can tell you that we got a call from Pfizer roughly April to 10th, right in that zone, requesting that we consider

1:35.0

participation. And we had our first Zoom meeting that Wednesday. So it was essentially two

1:43.1

weeks of round clock work to get this study up and running

1:49.7

and to the point last week where we put out the call to volunteers asking for recruits.

1:57.7

So are you saying that normally a process that could take, I don't know, a year, took four weeks?

2:05.1

A month. Yeah, that's exactly what I'm saying.

...

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