This is an IHeart podcast.

When news broke earlier this year that baby KJ, a newborn in Philadelphia,

had successfully received the world's first personalized gene editing treatment,

it represented a milestone for both researchers and patients.

But there's a gripping tale of discovery behind this accomplishment and its creators.

I'm Evan Ratliff, and together with biographer Walter

Isaacson, we're delving into the story of Nobel Prize winner Jennifer Dowdna, the woman who's helped

change the trajectory of humanity. Listen to Aunt CRISPR, the story of Jennifer Dowdena with

Walter Isaacson on the IHeart Radio app, Apple Podcasts, or wherever you get your podcasts.

Michael Lewis here.

My best-selling book, The Big Short,

tells the story of the build-up and burst of the U.S. housing market back in 2008.

A decade ago, the Big Short was made

into an Academy Award-winning movie.

And now I'm bringing it to you for the first time

as an audiobook narrated by yours truly.

The Big Short Story, what it means to bet against the market, and who really pays for an unchecked financial system, is as relevant today as it's ever been.

Get the Big Short now at Pushkin.fm slash audiobooks or wherever audiobooks are sold.

Welcome to Stuff You Should Know, a production of IHeartRadio.

Hey, and welcome to the podcast. I'm Josh, and there's Chuck and Jerry's here too, And this is stuff you should know. And what we've got on our hands today, Chuck, is a hot potato of a real deal geological mystery.

Hot potato? That's how Emily's family says potato. I think I would only say it when it's preceded by hot. I would only say it like, I wouldn't say, I'm going to have a baked potato. Like, you'd be out of your mind to say it like that. Nor would you say a hot potato. Like, what a square. Yeah, that is pretty square, isn't it? Get the stick out of your butt, fella. Loosen up. Right. Losen up.

Get the cardigan out from around your shoulders.

...