Inherited Trauma: The Hidden Reason Depression Runs In Your Family
Wellness + Wisdom Podcast
Josh Trent
4.8 • 913 Ratings
🗓️ 13 January 2026
⏱️ 66 minutes
🧾️ Download transcript
Summary
Is mitochondrial decline the hidden blueprint that decides how fast your body ages?
Josh Trent welcomes Dr. Brad Currier, PhD, Clinical Scientist, to the Wellness + Wisdom Podcast, episode 793, to unpack how mitochondrial health is passed through generations, why modern environments and sedentary living accelerate aging, how mitophagy and Urolithin A restore cellular energy, why gut health blocks or enables longevity, and how exercise plus targeted supplementation can fundamentally shift mood, vitality, and long term health from the inside out.
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In This Episode, Dr. Brad Currier Uncovers:
- (01:12) Why mitochondria are inherited from your biological mother
- (02:31) Mitochondria explained like you’re 10
- (03:37) What silently drains mitochondrial power
- (05:31) UV, pollution, toxins
- (08:36) The “seventh generation” lens
- (13:29) Why cells age before we “feel” old
- (17:31) Autophagy vs mitophagy
- (20:12) Urolithin A + the microbiome
- (32:33) Mitopure vs NAD/CoQ10
- (50:20) The Fundamentals of Health
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Transcript
Click on a timestamp to play from that location
| 0:00.0 | The Native Americans described the seventh generation principle. Seven generations previous actually impact the present moment. |
| 0:07.2 | If we had seven generations that were living in extreme bouts of stress, it impacts us. |
| 0:12.9 | Poor quality food, pollutants in our environment, they'll ultimately converge on mitochondria and have an impact on its ability to produce energy. |
| 0:21.3 | If there is a baby that's being created in utero in the mother and she herself is dealing with |
| 0:27.1 | extremely high levels of stress, the child could actually be wired at birth for hypervigilance. |
| 0:33.4 | When we have this accumulation of debris in our cells, they don't work as well. |
| 0:41.3 | They start releasing toxins that impact cells around them. Napoleon Hill said that when we keep the sewer systems dirty, |
| 0:44.3 | and when the sewer systems aren't able to purify, |
| 0:47.3 | it can actually start to compound in the mind. |
| 0:49.3 | The mind can become very weak. |
| 0:51.3 | It essentially atrophies the decision-making faculty in the mind. |
| 0:55.0 | Nature, that's the starting point. We didn't have any control over the hand we were dealt, but we |
| 1:01.0 | can do a tremendous amount within our lives to build off that starting point. |
| 1:10.0 | When it comes to mitochondria, my, yours, and everybody's is inherited only from our biological mother. |
| 1:19.1 | I find that fascinating. Can you explain that on a scientific level, but also on a personal level, |
| 1:24.7 | that we only inherit our mitochondria from our biological mother. |
| 1:28.6 | Yeah, it's fascinating. So our mitochondria are derived from our maternal parent. And what's really |
| 1:35.2 | neat about mitochondria is that for almost everything in our body, the DNA that makes the proteins |
| 1:40.9 | that actually do the activities in our cell is stored in the nucleus. So maybe that's |
| 1:46.5 | a term people have remembered, but the nucleus is really the center housing in our cells that has |
| 1:52.2 | that, you know, manuscript of life. It tells us how to make everything in our body. Mitochondria are unique |
| 1:57.6 | in that there's mitochondrial DNA, and actually most of, that's outside of the nucleus within the mitochondria. |
... |
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