Inherited Trauma: The Hidden Reason Depression Runs In Your Family

Wellness + Wisdom Podcast

Josh Trent

Education, Self-improvement

4.8 • 913 Ratings

🗓️ 13 January 2026

⏱️ 66 minutes

🔗️ Recording | iTunes | RSS

🧾️ Download transcript

Summary

Is mitochondrial decline the hidden blueprint that decides how fast your body ages?

Josh Trent welcomes Dr. Brad Currier, PhD, Clinical Scientist, to the Wellness + Wisdom Podcast, episode 793, to unpack how mitochondrial health is passed through generations, why modern environments and sedentary living accelerate aging, how mitophagy and Urolithin A restore cellular energy, why gut health blocks or enables longevity, and how exercise plus targeted supplementation can fundamentally shift mood, vitality, and long term health from the inside out.

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In This Episode, Dr. Brad Currier Uncovers:

[01:10] How to Optimize Mitochondrial Health

How our mitochondrial DNA is passed from mothers to children.
The functions of mitochondria in the human body.
How our environment affects our mitochondria.
Why UV radiation from the sun damages proteins in our cells.
How sedentary lifestyle impact mitochondrial health.

Resources:

[08:35] Intergenerational Mitochondrial Health

How mitochondrial health is impacted by multiple generations that came before us.
Why we're impacted by seven generations before us, and we impact seven generations after us.
The importance of nurturing our mitochondrial health.

Resources:

It Didn't Start with You by Mark Wolynn

[12:55] The Cause of Aging

What causes faster aging.
How our cells become unhealthy and age.
Why our cell turnover slows down as we age.
How mitochondria break down and impact our energy levels.

Resources:

781 Pedram Shojai | Anti-Aging Cult: Why Trying To Live Forever Devours Your Soul

[16:55] The Importance of Urolithin A

The role of postbiotics in digestion.
Why we need Urolithin A for optimal health.
How Urolithin A was discovered.

Resources:

Outwitting The Devil by Napoleon Hill

[20:55] You Need to Fix Your Microbiome

Why we have to take supplements to maintain our health.
How the microbiome blocks production of Urolithin A.
Why most people's gut microbiome is damaged.
How our gut microbiome lacks diversity compared.

[24:15] Gut-Brain Axis

How the gut-brain axis is linked to many diseases.
Why mitochondria can impact different systems of the body.
The importance of supplementing Urolithin A.
Why food cannot help us produce more Urolithin A.
How aging affects protein absorption.

[29:35] Activate Mitophagy to Stop Aging

Why Mitopure is the only clinically proven supplement to activate mitophagy.
The three phases of the mitochondria's life cycle.
Why removing cellular residue prevents aging.
How healthy mitochondria can help us live a better life.
Why renewing cellular energy requires consistency.

[36:05] Scientific Data Behind Mitochondrial Health

How mitochondrial health impacts mood and mental health.
Why Timeline Nutrition continues running new clinical studies.
How repeated scientific research proves whether something truly works or not.
Why they publish all of their studies online.

[43:40] The Power of Exercise

Why professional athletes have a higher risk of heart attack.
How exercise is the best tool for health and longevity.
Why combining Mitopure with exercise increases mitochondrial health.
How weightlifting helps us create new cells.

[50:20] The Fundamentals of Health

How Brad takes care of his own health.
Why exercise is the most important tool for him.
The role of a good diet and sleep in our health.

[55:20] Change Is Counter-Intuitive

Why change can feel counterintuitive at first.
The importance of allowing ourselves to feel uncomfortable.
How we can't often know for sure what tools or supplements are best for us.

"Poor quality food and pollutants in our environment ultimately converge on the mitochondria and have an impact on its ability to produce energy. When we have this accumulation of debris in our cells, they don't work as well and they start releasing toxins that impact cells around them. " — Dr. Brad Currier, PhD

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About Dr. Brad Currier, PhD

Inherited Trauma + Mitochondria: The Hidden Reason Depression Runs In Your Family

Brad Currier, PhD, is a clinical scientist specializing in mitochondrial health, cellular aging, and metabolic resilience.

With a background in translational research and applied clinical science, Brad focuses on how mitochondria, lifestyle inputs, and environmental stressors influence energy production, longevity, and disease risk.

His work bridges cutting-edge science with real-world application, helping people understand how to protect and optimize their cellular engines for sustained health, performance, and resilience.

Transcript

Click on a timestamp to play from that location

0:00.0	The Native Americans described the seventh generation principle. Seven generations previous actually impact the present moment.
0:06.9	If we had seven generations that were living in extreme bouts of stress, it impacts us.
0:12.9	Poor quality food, pollutants in our environment, they'll ultimately converge on mitochondria and have an impact on its ability to produce energy.
0:21.4	If there is a baby that's being created in utero in the mother and she herself is dealing
0:26.9	with extremely high levels of stress, the child could actually be wired at birth for hypervigilance.
0:33.4	When we have this accumulation of debris in our cells, they don't work as well.
0:41.3	They start releasing toxins that impact cells around them. Napoleon Hill said that when we keep the sewer systems dirty,
0:44.3	and when the sewer systems aren't able to purify,
0:47.3	it can actually start to compound in the mind.
0:49.3	The mind can become very weak.
0:51.3	It essentially atrophies the decision-making faculty in the mind.
0:55.0	Nature, that's the starting point. We didn't have any control over the hand we were dealt, but
1:01.0	we can do a tremendous amount within our lives to build off that starting point.
1:10.0	When it comes to mitochondria, my, yours, and everybody's is inherited only from our biological mother.
1:19.1	I find that fascinating. Can you explain that on a scientific level, but also on a personal level,
1:24.7	that we only inherit our mitochondria from our biological mother.
1:28.6	Yeah, it's fascinating. So our mitochondria are derived from our maternal parent. And what's really neat
1:35.4	about mitochondria is that for almost everything in our body, the DNA that makes the proteins that
1:41.2	actually do the activities in our cell is stored in the nucleus.
1:45.8	So maybe that's a term people have remembered, but the nucleus is really the center housing
1:50.7	in our cells that has that, you know, manuscript of life. It tells us how to make everything in
1:55.7	our body.
	...

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