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Finding Genius Podcast

Infectious Neuroscience: A Technological Approach To Neurodegenerative Diseases

Finding Genius Podcast

Richard Jacobs

Medicine, Health & Fitness

4.41K Ratings

🗓️ 17 May 2025

⏱️ 46 minutes

🧾️ Download transcript

Summary

Research in the past has indicated that neurological disorders such as Alzheimer's disease are non-infectious. But what if it was possible to catch a brain infection? Joining us to discuss this fascinating topic is Dr. Or Shemesh, an expert working to build and utilize new technologies to study and reverse brain disease…

Dr. Shemesh is an Assistant Professor at the University of Pittsburgh School of Medicine, Departments of Neurobiology and Bioengineering. Here, he works in a cutting-edge field called "Counter Disease Engineering" – otherwise known as a technological approach to understanding diseases of the nervous system. 

In this conversation, we cover:

  • The major causes of inflammation.
  • The unique connection between nervous system diseases and infectious agents. 
  • How microbes impact our overall health. 
  • How brain pathogens are potentially connected to Alzheimer's. 

You can learn more about Dr. Shemesh and his work here!

Episode also available on Apple Podcasts: http://apple.co/30PvU9C

Transcript

Click on a timestamp to play from that location

0:00.0

Forget frequently asked questions.

0:02.2

Common sense.

0:03.1

Common knowledge.

0:04.1

Or Google.

0:04.7

How about advice from a real genius?

0:06.9

95% of people in any profession are good enough to be qualified in license.

0:11.2

5% go above and beyond.

0:13.1

They become very good at what they do.

0:14.9

But only 0.1%.

0:16.5

A real geniuses.

0:18.2

Richard Jacobs has made it his life's mission to find them for you.

0:22.2

He hunts down and interviews geniuses in every field, sleep science, cancer, stem cells,

0:27.1

ketogenic diets, and more.

0:28.6

Here come the geniuses.

0:30.3

This is the Finding Genius podcast with Richard Jacobs.

0:37.2

Hello, this is Richard Jacobs with the Finding Genius podcast. My guest is O'R Shamesh, Ph.D.

0:43.7

He's a principal investigator. He has his own lab called the Shemesh Lab at University of Pittsburgh.

0:49.5

We're going to talk about something interesting, infectious neuroscience.

0:52.5

So this is the ever-growing likelihood that

0:56.9

certain diseases we thought that may not come from an infectious source actually may,

1:02.6

Alzheimer's, other neurological disorders. So I think this will be a very interesting call. And welcome

1:08.4

for. Thank you. Thank you. Happy to be here. Hi, Richard.

...

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