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Finding Genius Podcast

Impacts of Preterm Birth on Cardiovascular Health: Adam Lewandowski Discusses His Research

Finding Genius Podcast

Richard Jacobs

Medicine, Health & Fitness

4.41K Ratings

🗓️ 14 July 2020

⏱️ 29 minutes

🧾️ Download transcript

Summary

Professor Lewandowski studies effects of pregnancy complications like preterm birth on heart development and other bodily systems and organs.

In this podcast, he discusses preterm cardiology and possibilities of heart disease. He explains

  • How the medical community defines and categorizes preterm stages,
  • What preterm heart development looks like compared to in utero, and
  • What studies are being done to identify interventions that might improve long-term cardiovascular health for preterm children.

Adam Lewandowski is a university research lecturer and British Heart Foundation Intermediate Research Fellow at the University of Oxford in the Division of Cardiovascular Medicine, Radcliffe Department of Medicine. As neonatal clinical care has advancement to increase survival rates of preterm babies, more focus is on long-term connections between preterm development and heart disease.

Professor Lewandowski explains that babies born as early as 22 weeks survive, with a 60 to 70% survival rate within that cohort. He describes preterm development with a cardiology lens, explaining how changes in pressure effect functioning pulmonary resistance. It's common to see an increase in hypertrophic cells and thickening ventricular walls with smaller cavities leading to reduced myocardial functional reserve.

Dr. Lewandowski also touches on causes of preterm birth like genetic factors, preeclampsia, infections, obesity, and smoking. He addresses the challenges of preterm care such as monitoring and maintaining lung function, providing nutrition and food, and keeping them infection free.

Finally, he discusses chances of adult heart disease and other issues regarding cardiovascular health as well as studies to assess interventions like exercise and nutrition. He explains the importance of monitoring these patients as they grow into adulthood to catch any issues like hypertension early. He reminds listeners that long-term concerns often take a back seat at the neonatal stage because all efforts go to keeping these preterm babies alive.

For more about Dr. Lewandowski, see his lab's website at www.rdm.ox.ac.uk/about/our-divisions/division-of-cardiovascular-medicine/division-of-cardiovascular-medicine-research/lewandowski-group.

For other resources on these issues, look for good charity websites like the March of Dimes

Available on Apple Podcasts: apple.co/2Os0myK

Transcript

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0:00.0

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0:25.0

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0:30.3

This is the Finding Genius Podcast.

0:33.0

That is Richard Jacobs.

0:35.0

Hello, this is Richard Jacobs with the Finding Genius Podcast.

0:41.0

I have Adam Lewandowski., he's a university research lecturer and

0:45.8

British Heart Foundation research fellow. He's at the Oxford Cardiovascular

0:50.2

Clinic Clinical Research Facility, C to CRF the division of

0:54.2

cardiovascular medicine is from the US he sounds like it at least or Canada but he's

1:00.4

over in England so Anna I'm thanks for coming.

1:02.8

Hi thank you yeah so I'm Canadian.

1:05.4

Okay. Yeah, but I moved to the University of Oxford in 2009 to come take my start my PhD studies so I've been here for

1:17.5

almost 11 years now. Oh wow. What's the focus of your work? So the main area of my work is looking at the effect of pregnancy complications,

1:30.0

so specifically related to things like pre-term birth, so being born early, and how that affects heart development and the interaction with other systems, organs, so things like the brain liver and blood vessels and

1:47.3

lungs and how all of those things are changed within people born pre-term.

1:52.2

So pre-term?

1:52.8

So pre-term birth is it divided into like very early pre-term,

...

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