Immunocompromised and Covid, Summer SciFi Reading. June 18, 2021, Part 2
Science Friday
Science Friday and WNYC Studios
4.4 • 6.3K Ratings
🗓️ 18 June 2021
⏱️ 47 minutes
🔗️ Recording | iTunes | RSS
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| 0:00.0 | This is Science Friday. I'm Iroflato. Later in the hour, we kick off our summer of sci-fi with some bookpicks for your summertime reading. |
| 0:08.8 | But first, across the country, vaccination numbers are slowly ticking up. That's the good news. |
| 0:15.1 | Bad news is that some people may not be well protected, even if they do get the vaccine. These are people with compromised |
| 0:22.4 | immune systems. It could be due to another illness or due to immune suppressing drugs taken for |
| 0:29.3 | other medical conditions, such as a transplant. The problem is immunocompromised people may not mount a strong |
| 0:37.1 | antibody response to the vaccines, may not be |
| 0:40.3 | able to fight off the disease. Joining me now to talk about what options immunocompromised people may have |
| 0:46.3 | to deal with are my guests. Dr. John Mellers, distinguished professor of medicine at the University |
| 0:51.4 | of Pittsburgh, and chief of the Division of Infectious Diseases |
| 0:54.9 | at UPMC, and Dr. Lindsay Ryan, an internist at UC San Francisco. She is immunocompromised and wrote |
| 1:03.1 | about this problem in a recent issue of the Journal of the American Medical Association. Thank you |
| 1:08.7 | for joining us. Thanks so much for having me on the show. |
| 1:12.3 | Thanks, Ira. You're welcome. John, let's begin with you. Let's start with a definition. |
| 1:17.6 | What does it actually mean to be immunocompromised? It means very broadly that one's immune system |
| 1:25.4 | is not normal. That can have very different features |
| 1:30.3 | depending on what component of the immune system |
| 1:34.1 | is not normal. |
| 1:36.8 | For example, and in the context that we're talking about, |
| 1:41.0 | which is vaccine response, |
| 1:44.0 | lymphocytes are key, and there are two key types of lymphocytes, B cells that make |
| 1:52.0 | antibodies, and T cells that help B cells make antibodies. |
| 1:57.6 | And if you're deficient in either of those, you may not respond to a vaccine like somebody |
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