Immune reprogramming for cancer, and squeaky shoe science

The Naked Scientists Podcast

Dr Chris Smith

Science Radio, Engineering, Naked Scientists, Natural Sciences, Technology, Life Sciences, Health & Fitness, Medicine, Science

4.6 • 957 Ratings

🗓️ 6 March 2026

⏱️ 32 minutes

🔗️ Recording | iTunes | RSS

🧾️ Download transcript

Summary

Coming up, we explore how CAR-T cell therapy is revolutionising personalised cancer treatment. Plus, how NASA's DART mission tested Earth's asteroid defence, what we are learning about the benefits of breastfeeding for mother and baby health, and we delve into the physics behind squeaky shoes... Like this podcast? Please help us by supporting the Naked Scientists

Transcript

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0:00.0	All engine running.
0:03.3	Absolutely genius.
0:04.2	Welcome.
0:05.0	Welcome.
0:05.9	This is the show where we bring you science.
0:07.8	What that essentially means is.
0:09.3	Discovery is advanced.
0:10.3	Research.
0:11.5	Technology.
0:12.3	Unbelievable.
0:13.4	Without further ado, this is the naked scientist.
0:17.8	Hello, welcome to the Naked Scientist, podcast, the program that brings you the biggest
0:21.6	breakthroughs and also talks to the major movers and shakers in the worlds of science, technology and medicine.
0:27.4	With me, Chris Smith.
0:28.9	Coming up, reprogramming immune cells to attack tumours, how suckling infant's mouths actually
0:35.1	talked to their mother's breast tissue to make milk
0:37.5	composition just right for them and the physics behind the squeaky noises that our trainers make
0:43.2	in the gym.
0:50.3	First this week, car tea cell therapy is a form of personalised medicine that works by genetically
0:56.3	modifying a patient's own immune T cells to reprogram them with a new T-cell receptor so they can
1:02.6	recognise and attack disease tissues. The concept has been around for several decades, but it was
1:07.7	only approved for clinical use back in 2017. Since then, though,
	...

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