IDENTIFYING the BIGGEST Challenge Each 2026 Opponent Presents to the Buffalo Bills & WHO Must Step Up

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4.8 • 1.4K Ratings

🗓️ 12 May 2026

⏱️ 30 minutes

🔗️ Recording | iTunes | RSS

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Summary

Joe Marino breaks down the single biggest challenge each 2026 opponent brings—think De’Von Achane torching defenses for the Dolphins, Patrick Mahomes always finding a way for the Chiefs, and Jahmyr Gibbs threatening to break away with the Lions. Every week looks like a new test for Josh Allen and company, with matchup nightmares on both sides of the ball. From Houston’s relentless edge rushers Danielle Hunter and Will Anderson, to the Rams’ dynamic pass game with Matthew Stafford and Davante Adams, Joe Marino highlights which parts of the Bills need to step up. Will the revamped wide receiver corps finally outpace tough secondaries like New England’s? Can the front seven slow down high-octane running backs? Get ready for a rapid-fire look at the matchups that could make or break Buffalo’s season.

Transcript

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0:00.0	The NFL schedule drops later this week, so we're going to break down the biggest challenge each Buffalo Bills opponent presents right now.
0:14.4	You are locked on bills, your daily Buffalo Bills podcast.
0:19.6	Part of the Locked on podcast Network, your team every day.
0:25.9	What's up, Bill's Mafia?
0:27.8	It's Joe Marino.
0:29.1	Today's episode is brought to you by GameTime.
0:31.3	Download the GameTime app.
0:32.7	Create an account and use code locked on for $20 off your first purchase.
0:37.6	Welcome in, folks.
0:38.9	On today's episode, we're going to break down each of the bill's opponents and identify
0:44.7	the single biggest challenge that they present to the Buffalo Bills and what function
0:51.8	of the Buffalo Bills, the onus is on to overcome that challenge.
0:58.0	So the bills play 14 different teams.
1:01.0	Of course, they're divisional rivals twice each.
1:04.6	And then you have the remaining teams on your schedule.
1:08.5	So we're going to break down all 14 teams and really just identify what that challenge
1:13.1	is and who the onus is on for the bills to overcome it.
1:16.9	So we'll start with the AFC East.
1:19.7	Then we'll work through the rest of the AFC opponents and finish things off with
1:24.1	the NFC slate.
1:26.4	Yesterday we went through my wish list for the 2026 schedule.
1:30.7	And then on our next episode, we'll talk about the quarterback matchups that exist on
	...

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