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The Naked Scientists Podcast

Huntingtons Disease

The Naked Scientists Podcast

Dr Chris Smith

Science Radio, Engineering, Naked Scientists, Natural Sciences, Technology, Life Sciences, Health & Fitness, Medicine, Science

4.6957 Ratings

🗓️ 21 April 2014

⏱️ 53 minutes

🧾️ Download transcript

Summary

In a special show from Cambridge and New Zealand, Hannah Critchlow investigates the research into Huntington's Disease. How has the search to correct a single gene enhanced our understanding of how the brain functions? How are sheep helping to unpick the pizzle of the human mind? Plus we visit a brain bank to find out how tissue donors are supporting the scientific research. Like this podcast? Please help us by supporting the Naked Scientists

Transcript

Click on a timestamp to play from that location

0:00.0

And the Hello and welcome to the naked scientists with me Anna Critchlow.

0:20.3

This week we're investigating Huntington's, a neurodegenerative disease that affects one

0:25.6

in every 30,000 people worldwide.

0:28.9

We'll be finding out how this disease is helping us to grasp the incredible scale of complexity of the human

0:36.0

brain. It's almost as if we climb to the top of Mount Everest thinking we're

0:40.1

going to solve this disease and then we see all the Himalayas before us which

0:44.8

are even higher. There's going to be several lifetimes of work to unravel the human

0:49.1

brain. How sheep are helping to come up with treatments for patients.

0:53.0

Plus, we'll visit a bank full of frozen human brains.

0:58.0

We have all our brain bank freezes isolated in rooms.

1:04.0

The tissue is kept in these biohazard bags.

1:07.0

I'll just open up one of them.

1:09.0

All to come.

1:11.0

The Naked Scientists Podcast is powered by UKfast.co.uk.

1:17.0

In order to explore Huntington's disease I spoke with people both in my home city of

1:26.7

Cambridge UK and I took to the skies for a

1:35.0

single-tune university using.

1:36.0

Huntington's disease is hereditary,

1:38.0

a single gene change that can be passed down generations

1:42.0

from mother or father to their children to cause a myriad of symptoms

1:46.9

varying widely from person to person, but with typical age of onset in middle age.

1:53.8

Because a single gene is to blame,

...

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