HRT, Hormones, and Midlife: What Every Woman Needs to Know Before Deciding with Dr. Mindy Pelz
The Resetter Podcast with Dr. Mindy
Dr. Mindy Pelz
4.7 • 1.4K Ratings
🗓️ 5 January 2026
⏱️ 50 minutes
🧾️ Download transcript
Summary
Hormone Replacement Therapy is back in the spotlight, and many women are asking the same questions: Is it safe? Is it right for me? And why does it still feel so confusing?
In this solo episode, Dr. Mindy Pelz breaks down what really happened after the Women's Health Initiative study, why the black box warning was added and later removed, and what newer research has clarified about HRT, timing, hormone type, and delivery method. She explains why lifestyle and metabolic health are the missing pieces in this conversation and why HRT should never be viewed as a standalone solution.
This episode is not about telling you yes or no. It's about helping you understand the science so you can make an empowered, informed decision with your doctor.
To view full show notes, resources mentioned, transcripts, and more, visit 👉 https://drmindypelz.com/ep321
Check out our community membership at 👉 https://resetacademy.drmindypelz.com
Please note our medical disclaimer.
Transcript
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| 0:00.0 | On this episode of the Resetter podcast, I want to talk about a really hot topic. |
| 0:10.1 | And this is not, this is, I should probably say no pun intended, because we have been |
| 0:15.2 | inundated with questions around the new enthusiasm for HRT. |
| 0:21.6 | We're seeing it in my reset academy. |
| 0:24.0 | We're getting a ton of questions from women of all ages there. |
| 0:27.8 | The interviews I've been doing for age like a girl, |
| 0:30.7 | I've been getting a ton of questions about it there. |
| 0:33.5 | And even in my own ladies nights out, |
| 0:36.3 | there seems to be a buzz about is H.R.T. good or is it not good? |
| 0:41.3 | So even though there's this incredible enthusiasm around it, what is it that we need to know? |
| 0:48.3 | So on this episode, I'm going to break the science down. |
| 0:53.3 | So I have gathered the most current research that's showing |
| 0:56.5 | both the pro and the con so that you can make your own decision. This is a really important |
| 1:02.2 | part. You making your own decision is probably the most important thing I can say. And I want to |
| 1:07.7 | talk through some of the lifestyle considerations, some of the blood work you want to look at. |
| 1:12.7 | And I'm hoping by the end of this podcast that you're going to have just the right amount of information to be able to make a smart decision for you. |
| 1:24.9 | So with that in mind, let's dive in. Now first, if you're like, why is she |
| 1:30.7 | talking about HRT all of a sudden? I do want to make a point out that last week, or depending |
| 1:37.1 | when you're listening to this, a couple of weeks ago, the FDA announced that they were removing |
| 1:43.7 | the warning label on hormone replacement therapy for |
| 1:47.3 | menopause. This was a huge win according to many health influencers and menopausal experts, |
| 1:55.8 | many of which I've brought you here on the Resetter podcast. And everybody was a buzz last week. But after that, |
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