How your gut affects your mental health

ZOE Science & Nutrition

ZOE

Nutrition, Science, Health & Fitness, Education

4.6 • 5.6K Ratings

🗓️ 10 November 2022

⏱️ 40 minutes

🔗️ Recording | iTunes | RSS

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Summary

In a lab in Ireland, a group of scientists stand around a stainless steel table. One of them is holding a device, not unlike a small turkey baster. His free hand plunges into a box on the table and retrieves a mouse. Using his device, he administers the brown solution within…rectally. This unfortunate soul has just received a fecal microbiota transplant. The donor was not another mouse but a human being. And the person in question had symptoms of severe depression. Jonathan speaks to John Cryan, author of the study that showed a relationship between gut and brain. In this episode, we learn more about his fascinating research, how microbes may affect our brain, and to eat to appease your gut bugs. John Cryan is a professor at University College Cork and a world-leading researcher into the relationship between our brain and our gut microbiome. Download our FREE guide — Top 10 Tips to Live Healthier: https://zoe.com/freeguide Timecodes: 00:00 - Introduction 02:05 - Quickfire questions 03:26 - Are there links between the gut and the brain? 06:31 - The gut-brain axis 09:17 - How do gut bacteria affect our brains? 11:12 - Why does John call the microbiome “the chamber of secrets”? 14:20 - Does the microbiome explain drug side effects? 15:51 - Are there links between our microbiomes and mental health? 20:40 - If we improve our microbiome health can we improve our mental health? 24:58 - Can food help improve the microbiome and thus improve mental health? 28:33 - Microbiome’s effect on behavior 29:54 - Actionable advice 34:43 - Microbiome in adolescence 37:18 - Summary 38:26 - Goodbyes 38:48 - Outro Episode transcripts are available here. Follow John: https://twitter.com/jfcryan Follow ZOE on Instagram: https://www.instagram.com/zoe/ This podcast was produced by Fascinate Productions.

Transcript

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0:00.0	Welcome to Zoe, Science and Nutrition, where world-leading scientists explain how their
0:04.9	research can improve your health.
0:14.8	If you're listening to this, you probably know there's a community of bacteria living
0:18.8	in your gut, and you already know how they impact your health, right?
0:24.0	You may be less aware that right now these microbes might be affecting your mood, your
0:29.2	brain speed, and even how your brain ages.
0:38.1	In a lab in Ireland, a group of scientists stand around a stainless steel table.
0:43.7	One of them is holding a device, not unlike a small turkey-based.
0:48.2	He inserts the tip into a vial of brown solution and sucks up a tiny sample.
0:54.9	His free hand plunges into a box on the table and retrieves a mouse to whom he administers
1:00.6	the solution.
1:02.1	Recktily.
1:04.9	This unfortunate soul has just received a fecal microbiota transplant.
1:10.3	The donor was not another mouse, but a human being, and the person in question had symptoms
1:16.1	of severe depression.
1:19.3	In the days and months after this procedure, the scientists kept a close eye on our rodent
1:23.4	friend and countless others who'd undergone the same procedure.
1:27.6	As it transpires, the microbes have had an effect.
1:32.5	These mice can no longer derive joy from food.
1:36.0	By demonstrating behavior change through microbial transfer, this study proved a relationship
1:41.2	between gut and brain.
1:43.2	Although using mice, this is evidence that the same could be true for humans.
	...

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