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NutritionFacts.org Video Podcast

How Ultra-Processed Foods Could Cause Disease: Changes in Structure

NutritionFacts.org Video Podcast

Michael Greger, M.D. FACLM

Alternative Health, Health & Fitness, Nutrition

4.8951 Ratings

🗓️ 1 June 2026

⏱️ 7 minutes

🧾️ Download transcript

Summary

Why does preserving the food matrix make a difference?

Transcript

Click on a timestamp to play from that location

0:00.0

In the past few videos, I covered the nutrient profile of ultra-processed

0:10.0

the industrial contaminants, the additives, both intentional and unintentional, as well as changes

0:17.0

in texture.

0:18.0

But what's this about food matrix? In the famous study that found that ultra-processed diets caused excess calorie intake

0:24.6

and weight gain compared to unprocessed diets, despite the fact that both diets were

0:28.6

matched for calories, sugar, fat, and fiber, suggested that it may be something about the

0:33.6

processing itself, such as the concentration of calories and the changes in texture

0:38.0

that allow the foods to be eaten so much faster.

0:40.9

But wait, how did the researchers match for fiber?

0:45.6

It's hard to imagine ultra-processed foods having much fiber.

0:49.9

Here are two representative dinners.

0:51.8

On the ultra-process side, non-fat yogurt, fruit in heavy syrup, baked potato chips,

0:57.3

a deli meat-and-cheas sandwich, and three cups of diet lemonade.

1:01.2

And the same number of calories, fat, and sugar, on the unprocessed side,

1:04.6

a southwestern entree salad with greens, beans, nuts, fruits, and vegetables.

1:08.8

How could the ultra-process meal possibly have the same amount of fiber?

1:12.6

What they did was sprinkle a fiber supplement into the yogurt and lemonade.

1:18.6

So technically both meals had the same amount of fiber, but that's not how fiber works.

1:25.6

A half century ago, the dietary fiber hypothesis was proposed, suggesting that fiber was the reason

1:32.3

that diets centered around whole plant foods were so protective against chronic disease.

1:37.3

Predictably, this gave rise to a multi-billion-dollar fiber supplement market.

1:42.3

People could just eat real food, but where's the money in that?

...

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