This episode is brought to you by Cozy Earth, Rupa Health, Essentia, and Athletic Greens. Stress has somehow become a perceived right of passage for adults in the US. Many people feel that if they’re not stressed, they’re not working hard enough. And almost all of us have had stress build throughout our lives, a combination of trauma, life experiences, and our state of mind. Today on The Doctor’s Farmacy, I’m excited to talk to Dr. Elissa Epel about the wide-ranging effects of chronic stress on our health and how to mitigate it to feel better and even slow the aging process. Elissa Epel, PhD is an internationally renowned health psychologist who focuses on how to live well and thrive with existential stress, despite the challenges we face personally and globally. She is a professor at UCSF and the director of UCSF’s Aging, Metabolism, and Emotion Center. She is the coauthor of the New York Times bestseller The Telomere Effect which is in 30 languages. Her new book is THE STRESS PRESCRIPTION: Seven Days to More Joy and Ease. This episode is brought to you by Cozy Earth, Rupa Health, Essentia, and Athletic Greens. Get 40% off your Cozy Earth sheets at cozyearth.com and use code MARK40. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. Right now you can get an extra $100 off your mattress purchase, on top of Essentia’s Black Friday sale, which will also take 25% OFF your mattress purchase. Go to myessentia.com/drmarkhyman to learn more. Right now when you purchase AG1 from Athletic Greens, you will receive 10 FREE travel packs with your first purchase by visiting athleticgreens.com/hyman. Here are more details from our interview (audio version / Apple Subscriber version): Uncertainty tolerance and finding comfort in the unknown (4:56 / 2:55) How our trauma history impacts our ability to tolerate uncertainty (7:06 / 5:00)  The difference between acute and chronic stress (14:07 / 12:00)  How our mind states impact how we experience stress (17:21 / 15:19)  The impact stress has on mitochondria (29:57 / 25:00)  Incorporating hormetic or “good” stress into our lives (31:57 / 27:00)  How meaning, purpose, and mindset impact our lives (37:00 / 34:20)  Taking a stress inventory of your life (51:29 / 46:40)  Telomere health and aging (56:47 / 52:12)  Mitigating stress at the start of your day (1:03:13 / 57:25)   Get a copy of The Stress Prescription: 7 Days to More Joy and Ease. Mentioned in this episode Sauna use as a lifestyle practice to extend healthspan