This episode is brought to you by Rupa Health, Mitopure, Sunlighten, and Thrive Market. As we age, our body’s natural antioxidant defenses slow down, driving chronic inflammation and diminishing overall health.  To combat inflammaging, scientists have been studying compounds that can reduce inflammation and oxidative stress in the body. One such compound is astaxanthin, a powerful, naturally occurring antioxidant with profound anti-inflammatory health benefits. Today on The Doctor’s Farmacy, I’m excited to talk to David M. Watumull all about astaxanthin and how it helps to combat some of the key hallmarks of aging—inflammaging, mitochondrial dysfunction, and cell signaling. David M. Watumull has more than twenty years of experience in product development, commercialization, and business management related to astaxanthin—a safe and powerful, naturally-occurring anti-inflammatory—for human health. He is the co-founder and CEO of AX3 Life, a consumer longevity company formed to help people be their best selves longer. AX3 Life targets inflammaging—a core hallmark of aging—at its source with AX3 bio-pure astaxanthin. He is also the COO of Cardax, a life sciences business focused on advancing pharmaceutical and nutraceutical applications of astaxanthin. This episode is brought to you by Rupa Health, Mitopure, Sunlighten, and Thrive Market. Rupa Health is a place where Functional Medicine practitioners can access more than 3,000 specialty lab tests from over 35 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. Mitopure is the first and only clinically tested pure form of a natural gut metabolite called urolithin A that clears damaged mitochondria away from our cells and supports the growth of new healthy mitochondria. Get 10% off at timelinenutrition.com/drhyman and use code DRHYMAN10 at checkout. When it comes to infrared saunas, my number one brand is Sunlighten. Right now, you can save up to $600 on your purchase. Simply visit Sunlighten.com/mark-hyman and mention my name, Dr. Hyman, to save. Thrive Market is offering 30% off your first order and a free gift worth up to $60 if you sign up now at thrivemarket.com/Hyman. Here are more details from our interview (audio version / Apple Subscriber version): Steps to reduce and manage oxidative stress and inflammation (4:18 / 2:25)  How astaxanthin targets key hallmarks of aging (7:02 /  4:35)  Life span benefits of astaxanthin (13:34 / 11:32)  How astaxanthin benefits joint, muscle, and cardiovascular health and cognitive function (15:09 / 13:26)  Where astaxanthin is found in nature (22:38 /  18:47)  The FOXO3 gene (27:54 / 24:05)  Astaxanthin for longevity and healthy aging (37:23 / 34:45)  Synthetic vs natural astaxanthin (39:54 / 36:03)  Learn more about the astaxanthin supplement AX3.