How to Naturally Boost GLP-1, Reduce Cravings, & Lose Weight Faster - With Dr. Karan Rajan

The Model Health Show

Shawn Stevenson

Fitness, Health & Fitness, Motivation, Wellness, Nutrition, Health, Sex, Selfhelp

4.8 • 7.2K Ratings

🗓️ 3 November 2025

⏱️ 62 minutes

🔗️ Recording | iTunes | RSS

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Summary

In the age of GLP-1 medications, there’s a lot of talk about what causes satiety. Because GLP-1 agonists aid in weight loss by mimicking your body’s natural hormones, there are certain lifestyle factors that can naturally activate the stimulation of GLP-1 in your body. Today, you’re going to learn about the science of satiety hormones and the truth about the gut-brain connection. On this episode of The Model Health Show, our guest is world renowned surgeon and educator, Dr. Karan Rajan. You’re going to learn about the important connection between the gut and the brain, the science of GLP-1 receptors, and specific foods you can eat to improve your health. Dr. Karan Rajan has a wealth of knowledge in the realm of gut health, and he has an interesting and entertaining way of explaining things that I know you’re going to love. Click play to learn more about satiety, gut health, and how to eat for better health. Enjoy! In this episode you’ll discover: How food can stimulate satiety hormones. (5:33) The two food groups you should eat to improve satiety. (6:43) Why eating healthy fats is critical for increased satiety levels. (10:35) The importance of flavonoids and polyphenols. (10:54) How environmental exposures impact immune health. (19:33) Why perception plays a role in taste. (23:13) The connection between overeating and eating too quickly. (31:45) What to consider about the anti-nutrients in plant foods. (32:58) Which system develops first in the human body. (34:45) The bidirectional connection between the brain and the gut. (35:56) Which foods to eat for better gut health. (45:47) How to add more fermented foods into your diet. (47:37) The role hydration plays in gut health. (55:51) Items mentioned in this episode include: Paleovalley.com/model - Use code MODEL for 15% off! Piquelife.com/model - Get exclusive savings on bundles & subscriptions! This Book May Save Your Life by Dr. Karan Rajan - Get your copy today! LoamScience.com - Learn more about helping your microbiome thrive! Connect with Dr. Karan Rajan Website / Podcast / Instagram / TikTok / YouTube Be sure you are subscribed to this podcast to automatically receive your episodes: Apple Podcasts Spotify Soundcloud Pandora YouTube This episode of The Model Health Show is brought to you by Paleovalley, & Pique. Use my code MODEL at Paleovalley.com/model to save 15% sitewide on nutrient dense snacks, superfood supplements, and more. Go to Piquelife.com/model for exclusive savings on bundles & subscriptions on cutting-edge solutions for your head-to-toe health and beauty transformation.

Transcript

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0:00.0	You are now listening to The Model Health Show with Sean Stevenson.
0:04.8	For more, visit the modelhealthshow.com.
0:09.6	The age of fat loss is upon us.
0:13.5	But for the age of fat loss to be initiated, it had to be preceded by the age of fat gain.
0:20.6	And so as our society is trying to figure this whole thing out,
0:24.7	we are also entering the age of fat loss related medications, including the hot on the streets,
0:32.9	GLP wants. Now, here's the rub, and you're hearing it here probably first. This is just one of
0:42.1	many to come because we have a vast array, dozens of other satiety-related hormones. And right now,
0:50.7	food manufacturers are proactively trying to find ways to add ingredients to their foods,
0:57.4	these ultra-processed foods, to work their way around the GLP1 medications.
1:04.7	So that even if you're taking one of these medications, you still want to have an extra
1:10.2	twinkie or you still want to have some extra potato chips
1:14.1	or pop tarts or sody pops. All right. Food scientists, they're not just going to take this
1:21.0	sitting down. All right? They want you to sit down. Brilliant food scientists are proactively working to find ways to combat these new innovations.
1:32.7	And so simultaneously, drug manufacturers are designing more medications to address our other satiety-related hormone.
1:41.9	We got so many.
1:43.8	All right, gLP1 is just one. We've got
1:45.3	adipinectin, we've got C-C-K, we've got peptide, why, why, I can go on and on and on.
1:51.4	But today, in this very, very special and powerful episode, you're going to hear from a world-renowned
1:57.8	physician and surgeon with an expertise on gut health to share with us
2:03.9	how we must first and foremost work with our bodies and understanding, remembering that
2:11.2	GLP1 and all these other satiety-related hormones are produced naturally within our bodies
	...

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