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Finding Genius Podcast

How To Develop Safe And Effective Medications | Exploring The Next Generation Of Therapeutics

Finding Genius Podcast

Richard Jacobs

Medicine, Health & Fitness

4.41K Ratings

🗓️ 5 April 2023

⏱️ 27 minutes

🧾️ Download transcript

Summary

What will the next generation of medicine production look like? Dr. Govind Rao joins us today to discuss the importance of constructing safe and effective medications – standards that are harder to reach than one may think…

Dr. Rao is a Professor of Chemical and Biochemical Engineering, and the Director of the Center for Advanced Sensor Technology at the University of Maryland, Baltimore County. His research interests are primarily focused on how to enhance the production of protein-based therapeutics from the traditional fermentation and cell culture approach – something biopharmaceuticals have been doing for over 30 years.

In this episode, we discuss:

  • Experimentation that Dr. Rao's lab is doing. 
  • New technology that is enabling scientists to create proteins. 
  • The paradigm shift that may be on the horizon for therapeutic production.
  • Drugs that are most likely to improve in the near future. 

Wondering how Dr. Rao is contributing to the future of medicine and wellness? Join in now to see for yourself!

Want to find out more about Dr. Rao and his research? Click here now!

Episode also available on Apple Podcasts: http://apple.co/30PvU9C

Transcript

Click on a timestamp to play from that location

0:00.0

very similar to brewing beer, the conventional technology what you would do is take a cell and

0:06.0

you would have a gene is capable of producing a protein product and you would insert that clone

0:12.0

into the cell and then scale up the process by which I mean growing it in larger and larger vats

0:18.4

and then go through an elaborate procedure of recovering the product, the gene product that's being

0:25.2

expressed by the cells and this is something that's basic biology you and I are doing it all

0:30.4

the time we have our DNA instructions in our nucleus and all the proteins that make us up are

0:35.6

basically constantly being expressed so it's something that is fundamental to biology and

0:42.0

pretty much all organisms have that capability. Forget frequently asked questions. Common sense,

0:47.7

common knowledge or Google. How about advice from a real genius? 95% of people in any profession

0:53.9

are good enough to be qualified in license. 5%? Go above and beyond. They become very good at what

0:58.9

they do, but only 0.1% are real geniuses. Richard Jacobs has made his life's mission to find them

1:06.4

for you. He hunts down and interviews geniuses in every field. Sleep science, cancer, stem cells,

1:11.6

ketogenic diets and more. Here come the geniuses. This is the Finding Genius Podcast.

1:17.6

Richard Jacobs. Hello, this is Richard Jacobs with the Finding Genius Podcast,

1:25.7

now part of the Finding Genius Foundation. I have Govind Rao, he's a chemical and biochemical

1:30.8

engineering professor at University of Maryland and we're going to talk about his work about what's

1:35.9

called biologic medications on demand. So Govind, thank you so much for coming. Thank you for

1:40.6

having me Richard and I'm at the Baltimore County campus and I also run the Center for Advanced

1:46.2

Sensor Technology here. Okay, excellent. Tell me a bit about your background and then I want to

1:51.6

talk about the research that you're doing right now. So I'm a chemical engineer by training and then

1:57.1

more specialized into what's called biochemical engineering and my research has to do with how you

2:02.8

manufacture protein based therapeutics from the traditional fermentation and cell culture approach,

...

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