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The Human Upgrade: Biohacking for Longevity & Performance

How To Deal With The Fear Of Death (Ethics Of Longevity) : 1325

The Human Upgrade: Biohacking for Longevity & Performance

Dave Asprey

Fat, Health & Fitness, Meditation, Biohacking, Lifestyle, Diet, Science, Self-improvement, Fasting, Nutrition, Hacking, Fitness, Brain, Wellness, Education

4.67.3K Ratings

🗓️ 9 September 2025

⏱️ 62 minutes

🧾️ Download transcript

Summary

Most people spend their lives trying to outrun death instead of learning from it. This episode shows you why facing mortality directly can unlock resilience, forgiveness, gratitude, and peace while upgrading longevity, human performance, and even brain optimization. 


Watch this episode on YouTube for the full video experience: 

https://www.youtube.com/@DaveAspreyBPR 


Host Dave Asprey sits down with Suzanne O’Brien, RN—an end-of-life expert, hospice nurse, and founder of Doulagivers who has guided over 1,000 people through their final moments. She shares what the dying can teach the living about biohacking fear, letting go of unresolved trauma, and finding clarity before it’s too late. 


Together they explore how hacking your mindset around death transforms not only emotional well-being but also physical health, neuroplasticity, and metabolism. You’ll hear stories of people who discovered forgiveness and gratitude at the end of life, and how those practices directly influence mitochondria, sleep optimization, and longevity. They dive into the link between fear, stress chemistry, and chronic illness—and why tools like fasting, ketosis, cold therapy, supplements, nootropics, and functional medicine create the inner and outer resilience needed to face life fully. 


You’ll Learn: 

• Why fear of death silently undermines health, performance, and human potential 

• How forgiveness and gratitude rewire neuroplasticity and boost brain optimization 

• What hospice nurses know about consciousness and near-death experiences that science is only starting to confirm 

• How unresolved trauma shows up as physical pain and disease at the end of life 


Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. 


Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. 


Keywords: fear of death, hospice nurse, doulagivers, end of life planning, good death, forgiveness practice, gratitude science, near death experience, hospice care stories, emotional trauma release, spiritual awakening, conscious dying, home funeral, palliative care, death doula training, legacy planning, end of life rituals, soul agreements, dying process stages, compassionate care 


Thank you to our sponsors!  

 

Resources:  

• Suzanne’s Website: https://suzannebobrien.com/ 

• Get Suzanne's Book 'The Good Death': https://thegooddeathbook.com

• Danger Coffee: https://dangercoffee.com/DAVE15 

• Dave Asprey’s BEYOND Conference: https://beyondconference.com 

• Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated 

• Upgrade Collective: https://www.ourupgradecollective.com 

• Upgrade Labs: https://upgradelabs.com 

• 40 Years of Zen: https://40yearsofzen.com 


Timestamps: 

00:00 — Trailer 

01:05 — Introduction 

03:13 — End-of-Life Choices 

09:50 — Forgiveness & Suffering 

15:46 — Advice to Younger Self 

20:00 — What Makes a Good Death 

23:00 — Hospice Stories & Mystical Experiences 

33:05 — The Good Death Defined 

41:01 — Meaning & Purpose 

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Transcript

Click on a timestamp to play from that location

0:00.0

What if there was something you could add to your water to make you perform better, have more energy, and protect your cells from damage?

0:07.0

Hydrogen is the smallest molecule in the universe, and the only one that can get deep inside your cells, mitochondria, and even your DNA.

0:15.0

It fuels energy production, crushes oxidative stress, and supports sharper brain function.

0:20.0

Hydrogen's a gas so you can't take it as a pill,

0:23.4

so you either have to breathe it in or infuse it into your water. But your tap, bottled, or filtered

0:29.1

water doesn't have it. That's why I use the Echoflask. Echoflask is a hydrogen generator that

0:34.3

uses advanced electrolysis and a proprietary proton exchange membrane to

0:39.7

infuse your water with pure hydrogen. No chemicals, no pH change, just therapeutic science-backed

0:46.4

hydrogen. I've noticed more energy, faster recovery, less inflammation, and mental clarity that

0:52.5

lasts all day. Go to echo water.com slash Dave and use code Dave10 for 10% off your echo flask.

1:00.2

You'll feel the difference in days. This episode is recorded here in Austin, Texas, not in my studio because the air conditioning broke.

1:10.7

And this is Texas.

1:12.0

So I'm downstairs where the second air conditioner is not broken.

1:15.7

So hopefully you like the set because we just made it up for you.

1:19.3

So you do work with death.

1:23.2

Yes.

1:23.9

But you call your company douula Givers. I do.

1:28.3

Isn't that about being born, not about dying?

1:31.3

Yeah, there's so many similarities with helping a spirit, a soul come into this world,

1:37.3

like there is leaving this world, but yet you think about it, we're doing everything to help

1:41.3

those babies come in.

1:42.3

Sometimes we're preparing before people, we're even pregnant. We're not doing nearly the same, probably nothing for us helping

...

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