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Nutrition Facts with Dr. Greger

How to Control the Side Effects of GLP-1 Drugs

Nutrition Facts with Dr. Greger

Michael Greger, M.D. FACLM

Nutrition, Alternative Health, Health & Fitness

4.83.7K Ratings

🗓️ 1 May 2025

⏱️ 11 minutes

🧾️ Download transcript

Summary

Can “Ozempic face,” gastrointestinal distress, and nausea be mitigated?

This episode features audio from How to Control the Side Effects (Including “Ozempic Face”) of GLP-1 Drugs

Visit the video page for all sources and doctor’s notes related to this podcast.

 

Transcript

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0:00.0

We ask a lot of questions about our diet.

0:03.0

What's the right way to treat a chronic illness, fight off a virus, lose weight?

0:09.0

The problem is we get a lot of different answers.

0:12.0

Well, I'm here to help.

0:14.0

Welcome to the Nutrition Facts podcast.

0:16.0

I'm your host Dr. Michael Greger.

0:19.0

Today, in part three of our series on OZMPIC, we look at how to control the side effects

0:23.6

of GLP1 drugs.

0:25.6

It appears the vast majority of people prescribed GLP1 drugs stopped taking them in a matter

0:30.6

of months, but compare that to the older weight loss drugs.

0:34.6

Those had a 98% failure rate. In drug trials, most people taking these types of weight-loss drugs. Those had a 98% failure rate.

0:38.0

In drug trials, most people taking these types of weight-loss drugs started out obese and

0:42.3

ended up obese no matter how long they stayed on them.

0:45.3

But that's just on average.

0:46.8

Some people, despite being on high-dose-ozympic for years, actually ended up heavier than

0:51.8

when they started, and most remained overweight, but

0:55.1

a small fraction, some about 1 in 25, plateaued down at a normal weight.

1:01.4

1 in 25 doesn't sound like a lot, but obese individuals are rarely able to achieve

1:05.9

a normal weight without something drastic like bariatric surgery.

1:10.0

Only about 1 in 200 men with

1:11.5

class 1 obesity or 1 in 100 women, are able to find their way back to a normal weight,

1:16.7

so these drugs really can have a huge effect in a select few.

...

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