How to Catch Alzheimer’s Before It Starts, with Dr. Eric Topol

The Dr. Hyman Show

Dr. Mark Hyman

Health & Fitness, Nutrition, Medicine

4.6 • 8.7K Ratings

🗓️ 23 July 2025

⏱️ 101 minutes

🔗️ Recording | iTunes | RSS

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Summary

On this episode of The Doctor Hyman Show, I sit down with Dr. Eric Topol—renowned cardiologist, geneticist, and founder of the Scripps Research Translational Institute—to talk about the future of disease prevention. From AI diagnostics to genetic risk scoring, we explore the tools that could help stop Alzheimer’s and other chronic diseases before they start. This is one of the most hopeful conversations I’ve had about what’s ahead. Watch it on YouTube here. We discuss: • How new diagnostics and AI tools could help detect Alzheimer’s early • The key lab tests and biomarkers to know—and how to talk to your doctor about them • Why tracking your health data over time matters more than you think • What you can do to strengthen your immune system and lower disease risk We have more power than ever to take control of our health. This episode shows you where to start. View Show Notes From This Episode Get Free Weekly Health Tips from Dr. Hyman https://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Sign Up for Dr. Hyman’s Weekly Longevity Journal https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Join the 10-Day Detox to Reset Your Health https://drhyman.com/pages/10-day-detox Join the Hyman Hive for Expert Support and Real Resultshttps://drhyman.com/pages/hyman-hive This episode is brought to you by Seed, Pique, fatty15 and AirDoctor. Visit seed.com/hyman and use code 25HYMAN for 25% off your first month of Seed's DS-01® Daily Synbiotic. Receive 20% off FOR LIFE + a free Starter Kit with a rechargeable frother and glass beaker at Piquelife com/Hyman. Head to fatty15.com/hyman and use code HYMAN for 15% off your 90-day subscription Starter Kit.Get cleaner air. Right now, you can get up to $300 off at airdoctorpro.com/drhyman.

Transcript

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0:00.0	Coming up on this episode of the Dr. Hyman Show.
0:02.5	When you start to talk about preventing Alzheimer's and picking it up early,
0:07.4	how early can you start to see the Ptow changes?
0:11.4	Petow 217 is the very first one that goes up and it starts 20 years before mild cognitive impairment, 20 years.
0:19.4	Dr. Eric Topal is a world-renowned physician using data, tech, and deep insight,
0:24.6	to transform how we detect and prevent diseases like Alzheimer's before they even start.
0:29.6	There's so much data to show that that social isolation is a risk factor for neurodegenerative and cardiovascular and even cancer.
0:38.4	Strength training is a powerful drug and sleep is a powerful drug. They're better than most of the
0:42.6	drugs we have, actually.
0:48.0	In functional medicine, we always start with the gut. It's at the core of nearly every aspect of
0:52.8	health, from digestion and immune function to brain and skin health. Your gut microbiome regulates inflammation,
0:58.3	absorbs nutrients, and maintains the integrity of your gut barrier. That's why I take and recommend
1:02.6	seeds DSO-1 daily symbiotic, a next-level probiotic designed to go beyond digestion. With 24
1:08.1	clinically studied probiotic strains and a pomegranate-based prebiotic,
1:11.6	DSO-1, supports gut immune function, gut barrier integrity, and even heart health through the gut-liver
1:16.9	axis. But here's what's really exciting. Research now shows that gut health directly impacts
1:22.1	skin health through the gut-skin axis. DSO-1 contains targeted strains clinically validated to support clear, hydrated skin from within.
1:29.6	As a member of Seed's clinical board, I've seen the science behind their formulations.
1:33.6	And new research shows DSO1 supports short-chain fatty acid production, which is key for gut barrier
1:38.9	function, immune health, and healthy aging.
1:40.9	If you're ready to optimize your gut health, Seed is offering my community 25% off your first month. Just head to ced.com.com.com hymen and use code 25 hymen at checkout. That's seed.com hymen with code 25 hymen for 25% off your first month. I'm incredibly intentional about how I fuel my brain because whether I'm with patience, writing, or leading a team, focus and clarity matter. One of the most powerful tools I've added to my daily routine is Nandukha by Peak. Nanduka is a clinically
2:05.3	inspired neutropic adaptogen blend that delivers calm, sustained energy, and sharp mental focus
	...

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