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The Dr. Hyman Show

How Silent Inflammation Accelerates Aging with Dr. David Furman

The Dr. Hyman Show

Dr. Mark Hyman

Health & Fitness, Nutrition, Medicine

4.68.7K Ratings

🗓️ 21 December 2022

⏱️ 73 minutes

🧾️ Download transcript

Summary

This episode is brought to you by Rupa Health, BiOptimizers, and InsideTracker.


If you’re interested in health, you’ve heard the term inflammation quite a bit. But did you know there are different kinds of inflammation? Some of them are more alarming than others. Acute inflammation happens when you cut your finger and it gets red and a little swollen. This is helpful inflammation and usually resolves in about a week. But the inflammation that naturally happens as we age, called sterile-inflammation, sets us up for less resiliency against things like autoimmunity, cancer, and other forms of chronic disease. 


Today, I’m excited to dive deep into the topic of inflammation and its role in aging with Dr. David Furman. Dr. David Furman is Associate Professor and Director of the Bioinformatics Core at the Buck Institute for Research on Aging, as well as the Director of the Stanford 1000 Immunomes Project. He obtained his doctoral degree in immunology from the School of Medicine, University of Buenos Aires, Argentina, for his work on cancer immune-surveillance. During his postdoctoral training at the Stanford School of Medicine, Dr. Furman focused on the application of advanced analytics to study the aging of the immune system in humans.


This episode is brought to you by Rupa Health, BiOptimizers, and InsideTracker.


Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com.


Magnesium Breakthrough really stands out from the other magnesium supplements out there. BiOptimizers is offering my community 10% off, so just head over to magbreakthrough.com/hyman with code hyman10.


InsideTracker is a personalized health and wellness platform like no other. Right now they’re offering my community 20% off at insidetracker.com/drhyman.


Here are more details from our interview (audio version / Apple Subscriber version):

  • The origins of Dr. Furman’s unique thinking about the immune system and aging (7:21 / 3:58) 
  • Types of inflammation (11:13 / 8:02) 
  • How systemic chronic inflammation drives all of the hallmarks of aging (13:32 / 10:30) 
  • Causes of inflammation (18:24 / 13:46) 
  • The immunome and the 1000 Immunomes Project (26:31 / 21:14) 
  • How inflammatory age can be used to predict disease (33:13 / 27:12) 
  • Predicting frailty in individuals years before they become frail (35:54 / 30:37) 
  • Newly discovered biomarkers that can be used for early detection of age-related disease (38:54 / 32:02) 
  • How the iAge test will be used in the future (47:58 / 43:42) 
  • Learnings from centenarians (59:24 / 54:12) 


Learn more about the 1000 Immunomes Project.



Hosted on Acast. See acast.com/privacy for more information.

Transcript

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0:00.0

Coming up on this episode of the doctor's pharmacy every single one of the hallmarks of aging are driven by elevated systemic

0:09.4

inflammation in the body as a response to multiple triggers that have to do with how we treat our bodies.

0:18.1

Hey everyone, it's Dr. Mark. One of the most important tools I have for helping my patients

0:22.4

Optimizer Health is testing and that is why I love what root-by-health is doing.

0:26.8

Functional medicine testing can require placing orders with lots of different labs and it can kind of get really complicated for

0:33.6

Doctors and their patients to easily access results and keep track of everything.

0:37.4

But root-by-health has totally streamlined that process.

0:40.8

Looking at hormones, organic acids, nutrient levels, inflammatory factors, gut bacteria, and so many other internal variables can help us find the most effective path to health and healing.

0:51.0

I'm really excited about that now and I can finally take advantage of these tests.

0:54.9

Without the hassle of the confusion of so many multiple labs, root-by-health is the place for functional medicine practitioners to access more than 2000,

1:04.1

especially lab tests from over 20 labs like Dutch, vibrant America, Genova, great planes, and more.

1:09.1

It's 90% faster than you simplify the process of getting you the functional tests that you need and giving you more time to focus on your patients.

1:18.5

This is really a much needed option in the functional medicine space and it means better service for you and your patients.

1:23.7

You can check it out with a free lab demo with a Q&A or create an account at root-by-health.com. That's rupayhealth.com.

1:31.1

I'm all about using food first when it comes to nutrition, but there's certain nutrients I recommend everyone supplement with because it's simply impossible to get adequate amounts from your diet alone.

1:40.7

One example is magnesium, which are soils, well they're not too healthy and because there's no organic matter, they can't extract the magnesium from the soil, from industrial farming, which is a drag.

1:52.5

That leads to 50% less of these minerals in our food than there was 50 years ago.

1:58.3

Then of course we're doing things that cause us to lose magnesium like sugar, caffeine, fluoride, even stress, which none of us have, right?

2:07.5

80% of Americans are actually deficient in magnesium and that may mean insufficient. That's not a true deficiency, but just not enough for optimal functioning because magnesium is so important.

2:18.3

It's a huge problem for our health. Considering the pandemic of stress along with the pandemic of COVID that we're facing, we should all really be conscious about our magnesium intake because it activates the parasympathetic nervous system, which keeps us calmer and more relaxed.

2:33.3

Magnesium is crucial for more than 300 other chemical reactions in the body and impacts everything from metabolism to sleep, to neurologic health, energy, pain, muscle function, and lots more.

2:44.3

My favorite new magnesium is from a company called Bio Optimizers. Their magnesium breakthrough formula contains seven different forms, all of which have different functions in the body.

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