4.8 • 3.6K Ratings
🗓️ 3 July 2025
⏱️ 14 minutes
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| 0:00.0 | Have you ever wondered if there are more natural ways to lower your high blood pressure, |
| 0:06.0 | guard against Alzheimer's, loose weight, feel better? |
| 0:08.7 | Well, it turns out there is. |
| 0:12.1 | Welcome to the Nutrition Facts podcast. |
| 0:14.6 | I'm your host, Dr. Michael Greger. |
| 0:17.5 | Did you know the secretion of melatonin appears to progressively decline with age, |
| 0:22.6 | dropping as much as 70 percent to a middle age and older age? |
| 0:26.6 | Here's our first story. |
| 0:28.6 | Some experts recommend melatonin as a first-line agent to treat insomnia in older adults. |
| 0:34.6 | The world's sleep society disagrees due to its low efficacy. |
| 0:39.6 | Subjectively, people report better sleep, though objectively, a meta-analysis of studies |
| 0:44.6 | found that melatonin only helped people get to sleep four minutes faster and extended |
| 0:49.5 | overall sleep duration by about 13 minutes. |
| 0:52.8 | If you do want to try melatonin to help with sleep, older adults are advised to use |
| 0:57.0 | the smallest effective dose, an hour before bedtime, starting perhaps at 0.3 milligrams. |
| 1:04.0 | The 12 milligrams supplements in the market could produce levels in the bloodstream that |
| 1:08.0 | can be 200 times higher than normal nightly levels, |
| 1:11.6 | which raises safety concerns. |
| 1:13.6 | After all, melatonin used to be known as the anti-gonad hormone, |
| 1:18.6 | with humanocleven doses of just a milligram or two, |
| 1:21.6 | reducing the size of sex organs and impairing fertility in laboratory animals. |
| 1:25.6 | Furthermore, due to poor regulation of dietary supplements, |
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