The following Mark's Daily Apple article was written by Mark Sisson,

and is narrated by Tina Lehman.

How Going Primal can help with five common genetic mutations.

As I mentioned earlier this year,

our personal ancestry can help determine how we respond to certain dietary behavior, exercise, and lifestyle patterns. The big question remaining is this. Does going primal mesh with some of the more

common polymorphisms? Yes, the primal blueprint is a living

document. Its foundation rests on pre-agricultural human evolution, but by remaining flexible and

offering ample room for personalization, it acknowledges the fact that evolution has continued to occur.

Let's take a look at five genetic mutations and how the primal way of eating, living, and moving

can help mitigate their downsides.

Number 1. Aerobic Exercise Non-responder genes.

By now you've likely heard of exercise non-responders, people who

don't respond to cardio the way they're supposed to. Rather than experience health and fitness

benefits, an exercise non-responder might see no changes, or even detrimental ones when they exercise.

These non-responders seem to cluster in families

an indication of genetic influence. Aerobic exercise non-responders are the most common, whereas

about 85% of the population experiences big improvements in VO2 max after sustained endurance training, about 15% do not.

In some people, endurance training can even degrade their health.

They actually experience worsened insulin sensitivity, lower HDL, and elevated blood pressure when they train.

If a person is an aerobic non-responder, they do the work but see

little benefit unless they really up the intensity and duration of their aerobic training.

This means they have to lapse into chronic cardio territory just to get the benefits, and that

...