How Agatha Christie Used Chemistry To Kill (In Books)
Science Friday
Science Friday and WNYC Studios
4.4 • 6.3K Ratings
🗓️ 18 August 2025
⏱️ 18 minutes
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| 0:00.0 | Hey, it's Flora Licksman and you are listening to Science Friday. |
| 0:06.8 | Today in the podcast, death by poison, with the mistress of mystery, the Duchess of Death, |
| 0:13.8 | the Queen of Crime, Agatha Christie, who happened to be a chemistry nerd. |
| 0:18.3 | You really have to be quite picky to find fault in her use of poisons. |
| 0:26.1 | She is absolutely top quality in her scientific accuracy. |
| 0:32.3 | In about half of Agatha Christie's stories, poison is the murder weapon of choice. Dr. Catherine Harcup, |
| 0:39.6 | chemist-turned-author, explored those poisons in a new book, V's for Venom, Agatha |
| 0:45.1 | Christie's Chemicals of Death. Catherine, welcome back to Science Friday. Thank you for having me. |
| 0:51.3 | Catherine, this is not your first book about poisons or even about Agatha |
| 0:55.5 | Christie's poisons. What has brought you back to this well? Agatha Christie is so varied |
| 1:01.7 | in her choice of poisons. Everyone seems to think it's just arsenic in the ubiquitous cups of |
| 1:08.6 | tea served at the vicar's table. It's not that. She is so |
| 1:13.3 | imaginative and creative, not just in the choice of poisons, but how they're deployed, how they're |
| 1:19.4 | detected, how signs are signalled to her readers and other characters within the book. So I had more than enough material to fill one book. |
| 1:31.0 | And you must love writing about the science of killing people. |
| 1:34.8 | Oh, who wouldn't? |
| 1:35.8 | Okay. |
| 1:37.4 | Well, how accurate is the poison science in Agatha Christie's books? |
| 1:41.9 | I have to say she is top-notch. |
| 1:47.2 | You really have to be quite picky to find fault in her use of poisons. There are certain examples where she speeds up the effects |
| 1:55.6 | or she exaggerates the detectability, perhaps. But it's, you know, you can understand that for the purposes |
| 2:02.9 | of a story. Nobody wants to read about eight hours of agonizing stomach cramps. We want to get on |
... |
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