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Nature Podcast

How a key Alzheimer's gene wreaks havoc in the brain

Nature Podcast

podcast@nature.com

News, Science, Technology

4.5893 Ratings

🗓️ 16 November 2022

⏱️ 30 minutes

🧾️ Download transcript

Summary

00:46 Artemis 1 is go!

NASA’s Artemis 1 mission has successfully reached Earth orbit. After weeks of delays and issues, and a nail biting launch, the rocket marks the first step in a new era of moon exploration, with plans to test a new way to return astronauts to the moon. We caught up with reporter for all-things-space, Alex Witze, for the latest.


News: Lift off! Artemis Moon rocket launch kicks off new era of human exploration

10:06 Research Highlights

The unlevel playing field in women’s football, and domed structures provide evidence for a biological origin of stromatolites.


Research Article: Okholm Kryger et al.

Research Article: Hickman-Lewis et al.


12:39 A mechanistic link for an Alzheimer’s gene

Alzheimer’s disease is a form of dementia that affects millions of people every year. Whilst the biggest risk factor of late-onset Alzheimer’s is age, there are a number of genes that have been implicated. How exactly these genes underpin this disease is unclear, but new research may now reveal how one of them does so, by affecting the myelination of neurons. The authors hope this work may help uncover treatments for Alzheimer’s.


Research Article: Blanchard et al.

News and Views: Alzheimer’s risk variant APOE4 linked to myelin-assembly malfunction


20:44 Updates from COP27

The second week of the 27th UN Climate Change Conference is underway, as policymakers and scientists try to come together to tackle climate change. Flora Graham, senior editor at Nature is in Egypt at the conference and we caught up with her for the latest.


News: ‘Actions, not just words’: Egypt’s climate scientists share COP27 hopes

News: Carbon emissions hit new high: warning from COP27


Subscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.


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Transcript

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0:50.2

Search the Open University to find out more.

0:55.3

The Open University, the future is open.

1:02.4

Nature.

1:06.7

In an experiment, I don't know yet.

1:08.6

Why is Blight so far?

1:10.5

Like, it sounds so simple. They had no idea. But now the data's people. I have known yet. Why is blight so far? Like, it sounds so simple.

1:11.7

They had no idea.

1:13.2

But now the data's...

1:14.4

I find this not only refreshing, but at some level astounding.

1:22.1

Nature.

1:24.1

Nature.

1:26.1

Welcome back to the Nature podcast.

1:28.9

This week, a genetic link for late-onset Alzheimer's...

...

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