Hope in the fight against deadly prion diseases, and side effects of organic agriculture

Science Magazine Podcast

Science Podcast

News Commentary, News, Science

4.2 • 791 Ratings

🗓️ 21 March 2024

⏱️ 36 minutes

🔗️ Recording | iTunes | RSS

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Summary

New clinical trials for treatments of an always fatal brain disease, and what happens with pests when a conventional and organic farm are neighbors First up on this week’s show, a new treatment to stave off prion disease goes into clinical trials. Prions are misfolded proteins that clump together and chew holes in the brain. The misfolding can be switched on in a number of ways—including infection with a misfolded prion protein from an animal or person. Staff Writer Meredith Wadman talks with host Sarah Crespi about new potential treatments—from antisense nucleotides to small molecules that interfere with protein production—for these fatal neurodegenerative diseases. Next on the show: Freelance producer Katherine Irving talks with Ashley Larsen, associate professor of agricultural and landscape ecology at the University of California, Santa Barbara, about the effects of organic farms on their neighbors. If there are lots of organic growers together, pesticide use goes down but conventional farms tend to use more pesticides when side by side with organic farms. This week’s episode was produced with help from Podigy. About the Science Podcast Authors: Sarah Crespi; Katherine Irving; Meredith Wadman LINKS FOR MP3 META Episode page: https://www.science.org/doi/10.1126/science.z91m76v Learn more about your ad choices. Visit megaphone.fm/adchoices

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0:37.0	Morgan State University, a Baltimore, Maryland, Carnegie R2 doctoral research institution,
0:42.3	offers more than 100 academic programs and awards degrees at the baccalaureate,
0:47.3	master's, and doctoral levels, is furthering their mission of growing the future, leading the world.
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1:12.5	ascension to R1, visit Morgan.edu slash research. This is the science podcast for May 22nd,
1:25.0	2024. I'm Sarah Crespi. First up, hope in the field of deadly prion diseases.
1:30.3	Priyons are these misfolded proteins that clumped together and chew holes in the brain.
1:35.7	The misfolding of these normal proteins can be switched on in a number of ways.
1:40.7	Genetics, spontaneous folding, and infection, with a misfolded preon
1:46.3	from another animal or person. Staff writer Meredith Wadman walks me through new potential
1:51.8	treatments for these always fatal neurodegenerative diseases. Next up on the show, producer
1:58.0	Catherine Irving talks with researcher Ashley Larson about the effects
2:01.7	of organic farms on their neighbors. If there are very few organic farms, conventional farms
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