Hello and welcome to the Zero to Finals podcast. My name is Tom and in this episode I'm going

to be going to be going through Hennock-S-Lin-Purra, or H-S-P. And you can find written notes on this topic

at zero-definals.com slash HSP or in the rheumatology section of the zero-definals pediatrics book.

So let's get straight into it.

Henoxonline purepura or HSP is an IGA vasculitis that presents with a purpurek

affecting the lower limbs and buttocks in children.

Inflammation occurs in the affected organs due to IGA or immunoglobulin A deposits in the blood vessels.

It affects the skin, kidneys and the gastrointestinal tract.

The condition is often triggered by an upper airway infection or gastroenteritis prior to the development

of the HSP.

It's most common in children under the age of 10 years.

The four classic features to remember are Popura, which occur in 100% of children, joint pain,

which occurs in 75% of children, joint pain which occurs in 75% of children, abdominal pain

which occurs in 50% of children, and kidney impairment which occurs in 50% of children who

have the condition.

The rash is caused by inflammation and leaking of blood from small vessels under the skin,

forming purpura.

Purpura are red-purple lumps under the skin that contain blood.

These are non-blanching, meaning that HSP is a cause of a non blanching rash.

Let's talk in more detail about the features.

Pupura are seen in practically 100% of patients with HSP.

They are red-purple in colour and are palpable under the skin.

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