Hair Cells Could Heal Skin Sans Scars
Science Quickly
Scientific American
4.4 • 1.4K Ratings
🗓️ 6 January 2017
⏱️ 2 minutes
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| 0:00.0 | This is scientific American's 60 second science. |
| 0:05.0 | I'm Christopher Intagiyata. |
| 0:07.0 | Long ago, before band-aids or even medicine of any kind, |
| 0:11.0 | our ancestors evolved to heal cuts themselves. If he got sliced open, the body |
| 0:16.2 | blocked it up to prevent blood loss, water loss, infection. But as we gained that power, we |
| 0:22.1 | sacrificed something else. |
| 0:24.0 | So we've evolved to heal very quickly or as quickly as possible |
| 0:29.0 | at the expense of regenerating skin the way it used to be. |
| 0:34.4 | George Katsarellis, a skin biologist at the University of Pennsylvania, |
| 0:38.5 | who studies that newly healed skin, |
| 0:41.2 | also known as scars. |
| 0:42.9 | And the feature of scars is that they don't have |
| 0:45.8 | hair follicles, sweat glands, or fat. |
| 0:50.0 | In that observation lies a clue, which Katsorear Ellis and his team investigated in mice. |
| 0:55.0 | They found that when mice were injured, |
| 0:57.0 | hair follicles sometimes regenerated at the wound site. |
| 1:00.0 | And where hair cells appeared, fat cells did too, the fat that sits under normal skin as a cushion. |
| 1:06.5 | The bottom line is that the follicle has these almost magical powers where it's it's really normalizing the skin architecture. |
| 1:17.0 | Meaning hair cells are a good thing for reducing scarring. |
| 1:21.0 | In their latest work in the journal Science they isolated a growth factor called |
| 1:25.0 | BMP from the hair follicles. It's a signal the follicles send to |
| 1:29.4 | neighboring cells. They then exposed human scar cells to BMP in a dish. |
... |
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