meta_pixel
Tapesearch Logo
Log in
The Human Upgrade: Biohacking for Longevity & Performance

Hacking Weight Loss Resistance – Interventions With Dave – Diane Closser : 930

The Human Upgrade: Biohacking for Longevity & Performance

Dave Asprey

Nutrition, Fasting, Meditation, Fat, Self-improvement, Biohacking, Diet, Brain, Hacking, Wellness, Health & Fitness, Lifestyle, Education, Fitness, Science

4.67.4K Ratings

🗓️ 23 April 2022

⏱️ 45 minutes

🧾️ Download transcript

Summary

IN THIS EPISODE OF THE HUMAN UPGRADE...

… Dave talks with Diane Closser about weight loss resistance. You’ll find out how unexpected and insidious factors–both internal and external–may be affecting your body systems. That dysregulation can cause your body to hold onto excess weight. 

Diane Closser knows a lot about chemicals. She’s a chemist by profession and works as a Certified Lubrication Specialist and Certified Reliability Leader at a Division of General Motors.

She also has a personal history of mold and heavy metal exposure, e.g., bought fixer-upper 1972 house, played with Mercury as a kid, worked as a wet bench chemist analyzing heavy metal production products, and worked in tire industry.

She’s been on a journey to wellness for several years that’s included a search for real health solutions. 

There have been some wins: In 2020, she became particularly sensitive to chemicals, perfume, and laundry detergent. She says that ozone therapy cured her of her sensitivity and reversed her autoimmunity. And some setbacks: Her health deteriorated when husband was diagnosed with a brain tumor in 2011.

She also had her house treated with Chlorine dioxide; did low-dose allergen therapy and low-dose immunotherapy; and completed chelation therapy. 

Through it all, she’s experienced a frustrating weight loss resistance. She says she’s “been on every diet and med known to man” since her teenage years. 

Now in her mid-50s, she’s looking forward to a retirement that includes sailing and bringing tap, jazz, and ballet classes to senior citizens around the country. She wants to improve her health and have the energy to make her plans a reality.

In this “Interventions With Dave” episode, Dave and Diane look at her health concerns through a new lens. They examine possible causes of her inability to shed excess weight and discuss actionable next steps. 

  • Calorie counting 
  • Eating too little 
  • Environmental toxins
  • Chemical sensitivities
  • Mold 
  • Ozone
  • Histamine
  • Mast cells
  • Metal toxicity and chelation therapy
  • Brain fog
  • Thyroid
  • Testosterone in females
  • Mycotoxins
  • Detox pathways
  • Collagen


Note: The "Interventions With Dave” recommendations are designed to help you upgrade yourself and your biology so you can perform better at everything you do. They are not, however, a substitute for advice or treatment by a trained medical professional that may be needed for specific health conditions, illness or injury.

Listen to the Interventions With Dave series and don’t miss the “Links & Resources” section below for specific information. 

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Transcript

Click on a timestamp to play from that location

0:00.0

You're listening to the human upgrade with Dave Asprey.

0:06.0

Formerly, Bulletproof Radio.

0:12.0

You're listening to the human upgrade with Dave Asprey.

0:15.5

And this is a special interventions episode if this is your first time listening to it.

0:21.8

This is when I take a member of the upgrade collective, which is my private mentorship

0:26.4

and membership group, our upgrade collective.com is where you learn more about that.

0:31.1

And I work with them one-on-one on the air to work on biohacking, weird problems, or as

0:38.1

it turns out, what feels like a weird problem, but is exceptionally common.

0:43.0

You want to listen to this episode because it's going to teach you how to think about managing

0:48.3

your own biology.

0:50.1

Sometimes we talk about things that are medical.

0:54.6

I'm not sure exactly what that means, because we're talking about things that are life.

1:00.0

I am not a doctor.

1:01.1

I do not have a license in anything, except I am an ordained minister.

1:05.3

Actually, I did that once many years ago for six bucks.

1:09.8

Other than that, I don't have a license.

1:11.8

That means you can't take it away.

1:12.9

I am not practicing medicine and I'm not diagnosing, treating, or curing, but what I am doing

1:17.3

is teaching you, and in this case, Diane, how to think about a problem and maybe giving

1:22.5

you some good questions to go and ask your doctor.

1:24.9

Diane, welcome to the intervention.

1:27.2

Are you excited?

...

Please login to see the full transcript.

Disclaimer: The podcast and artwork embedded on this page are from Dave Asprey, and are the property of its owner and not affiliated with or endorsed by Tapesearch.

Generated transcripts are the property of Dave Asprey and are distributed freely under the Fair Use doctrine. Transcripts generated by Tapesearch are not guaranteed to be accurate.

Copyright © Tapesearch 2026.