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Science Quickly

Gut Microbes Help Keep Starved Flies Fecund

Science Quickly

Scientific American

Science

4.41.4K Ratings

🗓️ 26 April 2017

⏱️ 2 minutes

🧾️ Download transcript

Summary

Microbes living in the guts of fruit flies appear to influence the flies' food choice—and promote egg production, even under a nutrient-poor diet. Christopher Intagliata reports. Learn more about your ad choices. Visit megaphone.fm/adchoices

Transcript

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0:00.0

This is scientific American's 60 second science. I'm Christopher in Tagyatta.

0:07.0

Just like humans, fruit flies have to eat a balanced diet.

0:11.0

They need sugar to survive, they need amino acids to make eggs, to have stem cells

0:16.2

proliferate. They need salt, they need vitamins.

0:19.2

Carlos Roberto, a neuroscientist at the Champolemo Center in Portugal.

0:23.0

Yeast, he says, is a crucial component of the fly diet.

0:27.0

I always say yeast is the steak of the fly.

0:30.0

Take yeast away and the flies crave it.

0:33.0

They got to make those eggs.

0:34.7

Roberto and his team found that they could also elicit that yearning for yeast by simply removing

0:39.1

a few key amino acids from the fly's diet.

0:42.3

But that only worked in flies that had their gut

0:44.5

microbiome wiped out. Because here's the twist. When Ribero and his colleagues

0:49.0

restored the standard fly gut microbiome, amino acid-deprived flies did not seek out yeast to compensate.

0:55.5

It might seem like the gut microbes are actually

0:58.3

working against the fly's best interest,

1:00.5

blocking their instincts to seek out missing nutrients.

1:04.0

But what actually happened, Roberto says, is that flies with the gut microbes

1:08.0

maintained good egg production despite their nutritional deficiency,

1:12.0

suggesting that somehow the microbes help the flies adapt to nutrient poor conditions.

1:18.0

So somehow the microbes reprogram the metabolism of the fly to now cope better with an absence of a

1:26.6

mino acid in the diet and that might also lead then to the fly not having to

...

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