GLP-1s, Fasting, and the Future of Women’s Metabolic Health
The Resetter Podcast with Dr. Mindy
Dr. Mindy Pelz
4.7 • 1.4K Ratings
🗓️ 27 May 2026
⏱️ 68 minutes
🧾️ Download transcript
Summary
GLP-1 medications are changing the conversation around weight loss, metabolism, and women’s health. But are we asking the right questions about long-term health?
In this solo episode, Dr. Mindy Pelz breaks down the science behind GLP-1 drugs like Ozempic, Wegovy, and Mounjaro, including what they do well, where concerns are emerging, and how fasting mimics many of the same metabolic benefits naturally.
Dr. Mindy explores:
• The connection between GLP-1 drugs and muscle loss
• Why women over 40 need to think differently about metabolism
• New research linking GLP-1s to declining bone density
• How fasting impacts glucagon, ketones, and fat burning
• The importance of protein, refeeding, and resistance training
• Why metabolic flexibility matters more than rapid weight loss
• Natural ways to stimulate your body’s own GLP-1 production
This episode is not about fear or shame. It’s about helping you understand your options so you can make informed decisions for your body, your hormones, and your long-term health.
For more resources related to today’s episode, visit the podcast episode page: https://www.drmindypelz.com/ep341
Connect with Dr. Mindy:
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- Subscribe to Dr. Mindy’s newsletter
Disclaimer: This podcast is intended for educational and informational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making changes to your diet, fasting routine, or lifestyle.
Transcript
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| 0:00.0 | Okay, let me ask you a personal question. And this one is a really important one, which is when was the last time you had your vitamin D checked? And I'm saying this because in all my years of working with women, low vitamin D is one of the most consistent findings I see and one of the most consistently missed and vitamin D |
| 0:23.6 | matters for so many aspects of your health. We're talking about a deficiency that can show up as |
| 0:31.4 | hormonal imbalance, mood struggles, poor sleep, immune issues, even stubborn weight that won't budge no matter what you do. |
| 0:40.9 | But here's the part that most people don't know. |
| 0:43.8 | Taking an isolated D3 supplement isn't enough. |
| 0:47.5 | This isn't like just running down to the local store and grabbing some D3. |
| 0:51.4 | Your body actually needs D3 to be combined with very specific co-factors to actually |
| 0:58.2 | absorb and utilize vitamin D the way nature intended it. And most supplements on the market |
| 1:04.4 | don't include these co-factors. That's why I personally love Cataplex D from Standard Process. |
| 1:11.9 | It's a whole food supplement. |
| 1:14.4 | It's vitamin D complex, not just an isolated nutrient. |
| 1:19.3 | There's an incredible difference between checking a box and actually moving the needle on your health, |
| 1:25.8 | and this one really moves the needle. |
| 1:27.9 | In fact, in my clinic, we used to test vitamin D, and we could see with a product like |
| 1:34.4 | Cataplex D. We could see on lab work the vitamin D levels and people go up. |
| 1:40.9 | So you can learn more, and you can get yourself some vitamin D. You can test out CataplexD |
| 1:46.0 | at Dr. Mindy Pells.standard Process.com. Enjoy. |
| 1:52.0 | A lot of you are on the GLP1 drugs and you're getting great results with it and I'm not here to discredit the results |
| 2:03.7 | because millions of people are losing weight and improving their metabolic health with it. |
| 2:08.6 | And I also want to bring forward when we start to see that there are some side effects that might not be being presented to you or discussed, |
| 2:20.5 | I think it's really important that we fill in where these GLP ones may be creating some health |
| 2:28.1 | consequences. Beyond just, you know, obviously the scale loss is phenomenal. The A1C going down is incredible, but there's a few health things that we need to look at. |
... |
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