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Witness History

GLP-1: A breakthrough for diabetes and obesity

Witness History

BBC

History, Personal Journals, Society & Culture

4.41.6K Ratings

🗓️ 23 October 2025

⏱️ 11 minutes

🧾️ Download transcript

Summary

In the 1980s, scientists made a discovery that would eventually lead to the development of drugs now used worldwide to treat diabetes and to help people manage obesity through weight loss injections.

One of the key scientists behind this breakthrough was Svetlana Mojsov. She discovered that a hormone called GLP-1 (glucagon-like peptide-1) plays an important role in how our bodies respond to food.

Svetlana’s work laid the foundation for a drug company to develop treatments based on GLP-1 — first for type 2 diabetes, and later for weight loss. She tells Gill Kearsley her story.

Eye-witness accounts brought to life by archive. Witness History is for those fascinated by the past. We take you to the events that have shaped our world through the eyes of the people who were there. For nine minutes every day, we take you back in time and all over the world, to examine wars, coups, scientific discoveries, cultural moments and much more. Recent episodes explore everything from the death of Adolf Hitler, the first spacewalk and the making of the movie Jaws, to celebrity tortoise Lonesome George, the Kobe earthquake and the invention of superglue. We look at the lives of some of the most famous leaders, artists, scientists and personalities in history, including: Eva Peron – Argentina’s Evita; President Ronald Reagan and his famous ‘tear down this wall’ speech; Thomas Keneally on why he wrote Schindler’s List; and Jacques Derrida, France’s ‘rock star’ philosopher. You can learn all about fascinating and surprising stories, such as the civil rights swimming protest; the disastrous D-Day rehearsal; and the death of one of the world’s oldest languages.

(Photo: Injection pens. Credit: Carsten Snejbjerg/Bloomberg via Getty Images)

Transcript

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0:00.0

BBC Sounds, Music, Radio, podcasts.

0:07.3

Welcome back to the home of the oxymoron.

0:10.5

Evil genius.

0:11.6

He asked the newspaper to print his obituary early so he'd enjoy it.

0:15.5

That's like hiding at your own funeral.

0:17.1

Yeah, a big, great gig.

0:18.6

I'm Russell Kane.

0:19.6

Join me to weigh in on whether the biggest players in history are more evil or genius.

0:24.1

Becoming that rich, I'd say that at some level of genius.

0:26.4

It also helps that it's a long time ago, right?

0:29.4

It's like the podcast version of telling your kids the ice cream van plays music when it's out of ice cream.

0:34.9

Listen to Evil Genius on BBC Sounds.

0:41.8

Thank you. and it's out of ice cream. Listen to Evil Genius on BBC Sounds. Hello, this is witness history from the BBC World Service with me, Jill Kursley.

0:48.3

This is the podcast that takes you back to a key moment,

0:51.2

and we bring it all to live through incredible archive and the amazing memories

0:55.7

of a witness. The moment I'm taking you back to today is in the 1980s when scientists made

1:04.6

a breakthrough that would lead to the development of drugs that are now used globally to manage

1:10.0

diabetes and lose weight through

1:12.6

injections which were to become known as skinny jabs. You've seen the ads everywhere.

1:19.1

Off-brand versions of GLP1 drugs for weight loss. Brianna Sims lost 100 pounds in two years.

1:25.7

This medication has done wonders for me.

1:28.1

Many consider GLP1 drugs miracle fixes for obesity, type 2 diabetes and heart disease.

...

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