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BBC Inside Science

Gene Editing Ethics, Killer Whale Mummy's Boys and Ancient Hippo Butchery

BBC Inside Science

BBC

Technology, Science

4.51.3K Ratings

🗓️ 16 March 2023

⏱️ 30 minutes

🧾️ Download transcript

Summary

Chinese biophysicist He Jiankui caused international outrage when in 2018 when he used the gene-editing tool known as CRISPR Cas-9 to edit the genomes of two human embryos. That experiment, described by the Chinese Academy of Science and Technology described as ‘abominable’, resulted in the birth of twin girls. The experiment also landed Dr He in prison for three years. Now, out of prison and working for a company in Beijing that proclaims to offer “affordable gene therapy” – He Jiankui has been speaking in public. At an open bioethics event at the University of Kent last weekend, organisers invited the scientist to present his research and to face questions about his past experiments and his future plans. We spoke to event organiser Dr Joy Zhang about the reaction to event and to Professor Robin Lovell-Badge at the Crick Institute about the implications of CRISPR-CAS9 technology. A Hippo butchery site reveals that distant human ancestors have been using stone tools far longer than researchers previously thought. This archaeological site in Kenya revealed that ancient hominins Paranthropus have probably been using stone tools to prepare food and weapons since 2.9 million years ago. Professor Tom Plummer at Queens College, City University of New York take us through the discovery and what it reveals about hominin evolution. A study released this week reveals just how much of a burden sons are on killer whale mothers. Michael Wiess, research director at the centre for whale research, fills us in on their findings which are a product of nearly 40 years studying the southern resident Orca population. This long-term Whale census project began in the 70s, championed by researcher Ken Balcomb, who was passionate about understanding and protecting killer whales and who sadly passed away late last year. We hear from Ken and his team out on the water studying the southern residents, more of which can be found in BBC Radio 4 documentary The Whale Menopause. Presenter: Victoria Gill Producer: Emily Bird BBC Inside Science is made in collaboration with the Open University

Transcript

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0:00.0

Before you listen to this BBC podcast, I'd like to introduce myself.

0:03.7

My name's Stevie Middleton and I'm a BBC Commissioner for a Load of Sport Podcasts.

0:08.4

I'm lucky to do that at the BBC because I get to work with a leading journalist, experienced

0:12.2

pundits and the biggest sport stars.

0:14.3

Together we bring you untold stories and fascinating insights straight from the players'

0:18.5

mouths.

0:19.5

But the best thing about doing this at the BBC is our unique access to the sport in world.

0:25.0

What that means is that we can bring you podcasts that create a real connection to

0:28.8

dedicated sports fans across the UK.

0:31.2

So if you like this podcast, head over to BBC Sounds where you'll find plenty more.

0:35.8

Hello, dear Lightful Curious-Minded listeners.

0:38.3

This is the podcast edition of BBC Inside Science, originally broadcast on the 16th of February

0:43.6

2023.

0:44.6

I'm Victoria Gill.

0:46.5

This week we're digging up a 2.9 million year old stone toolkit that was used amongst

0:51.8

other things to butcher hippos and we're exploring the waters off the North Pacific coast

0:57.5

in search of killer whales that are revealing to biologists just how strong a family bond

1:02.4

can be.

1:03.9

But first, a CRISPR controversy.

1:07.0

Chinese biophysicist Hu Jiangquay caused international outrage when in 2018 he used the gene editing

1:13.1

tool known as CRISPR Cas9 to edit the genomes of two human embryos.

1:18.4

That experiment, broadly regarded as immoral, in fact the Chinese Academy of Science and

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